Skip to main content
Log in

Physical Exercise on Physical and Cognitive Function in Institutionalized Older Adults with Dementia: A Systematic Review

  • Published:
Ageing International Aims and scope Submit manuscript

Abstract

Dementia affects 50 million people worldwide and that number may treble by 2050, yet there are not many studies for this population, especially when they are living in homes for the aged. Regarding the latest published evidence, this study is a systematic review to investigate the effects of exercise on the physical, functional and cognitive capacity of institutionalized older adults with dementia. Searches were performed on Medline, PEDro, Lilacs, Scielo and Cochrane Library and this review follows the PRISMA guidelines, including only randomized controlled trials. The quality of studies was graded according to PEDro and the strength of the current evidence using the GRADE approach. This study is registered in PROSPERO (CRD42021232166). A total of ten studies met the inclusion criteria, with a sample of 876 participants with a mean age of 80 years old. The interventions were diversified, with multicomponent exercises, high-intensity functional training and activities of daily living training. The duration varied from three to six months and frequency averaged from two to three times a week. Studies suggested interventions with low technology, easy to implement and observed improvement in physical, functional and cognitive capacity, however there is no consistent evidence of which is the most suitable intervention. More studies should be encouraged considering the different types of dementia and levels of impairment, considering this is a diverse population that could benefit from physical exercise.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Blankevoort, C. G., van Heuvelen, M. J., Boersma, F., Luning, H., de Jong, J., & Scherder, E. J. (2010). Review of effects of physical activity on strength, balance, mobility and ADL performance in elderly subjects with dementia. Dementia and Geriatric Cognitive Disorders, 30(5), 392–402. https://doi.org/10.1159/000321357

    Article  PubMed  Google Scholar 

  • Brett, L., Traynor, V., & Stapley, P. (2016). Effects of Physical Exercise on Health and Well-Being of Individuals Living with a Dementia in Nursing Homes: A Systematic Review. Journal of the American Medical Directors Association, 17(2), 104–116. https://doi.org/10.1016/j.jamda.2015.08.016

    Article  PubMed  Google Scholar 

  • Bossers, W. J., van der Woude, L. H., Boersma, F., Hortobágyi, T., Scherder, E. J., & van Heuvelen, M. J. (2015). A 9-Week Aerobic and Strength Training Program Improves Cognitive and Motor Function in Patients with Dementia: A Randomized, Controlled Trial. The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry, 23(11), 1106–1116. https://doi.org/10.1016/j.jagp.2014.12.191

    Article  PubMed  Google Scholar 

  • Boström, G., Conradsson, M., Hörnsten, C., Rosendahl, E., Lindelöf, N., Holmberg, H., Nordström, P., Gustafson, Y., & Littbrand, H. (2016). Effects of a high-intensity functional exercise program on depressive symptoms among people with dementia in residential care: A randomized controlled trial. International Journal of Geriatric Psychiatry, 31(8), 868–878. https://doi.org/10.1002/gps.4401

    Article  PubMed  Google Scholar 

  • Broadhouse, K. M., Singh, M. F., Suo, C., Gates, N., Wen, W., Brodaty, H., Jain, N., Wilson, G. C., Meiklejohn, J., Singh, N., Baune, B. T., Baker, M., Foroughi, N., Wang, Y., Kochan, N., Ashton, K., Brown, M., Li, Z., Mavros, Y., Sachdev, P. S., & Valenzuela, M. J. (2020). Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI. NeuroImage. Clinical, 25, 102182. https://doi.org/10.1016/j.nicl.2020.102182

  • Camarano, A. A. E. & Mello, J. L. (2010) Cuidados De Longa Duração No Brasil: O Arcabouço Legal E As Ações Governamentais. In: Camarano, A. A. (Org). Cuidados De Longa Duração Para A População Idosa: Um Novo Risco Social A Ser Assumido? Instituto De Pesquisa Econômica Aplicada, Ipea, Rio De Janeiro V 1, Cap:2, P. 68–91.

  • Camarano, A. A. Kanso. S, Mello. J.L, Carvalho. D.F. As Instituições De Longa Permanência Para Idosos No Brasil. In: Camarano, A. A. (Org). Cuidados De Longa Duração Para A População Idosa: Um Novo Risco Social A Ser Assumido? 2010. V. 1 Cap. 7, P. 188–213.

  • Cancela, J. M., Ayán, C., Varela, S., & Seijo, M. (2016). Effects of a long-term aerobic exercise intervention on institutionalized patients with dementia. Journal of Science and Medicine in Sport, 19(4), 293–298. https://doi.org/10.1016/j.jsams.2015.05.007

    Article  PubMed  Google Scholar 

  • Casas-Herrero, A., Anton-Rodrigo, I., Zambom-Ferraresi, F., Sáez de Asteasu, M. L., Martinez-Velilla, N., Elexpuru-Estomba, J., Marin-Epelde, I., Ramon-Espinoza, F., Petidier-Torregrosa, R., Sanchez-Sanchez, J. L., Ibañez, B., & Izquierdo, M. (2019). Effect of a multicomponent exercise programme (VIVIFRAIL) on functional capacity in frail community elders with cognitive decline: Study protocol for a randomized multicentre control trial. Trials, 20(1), 362. https://doi.org/10.1186/s13063-019-3426-0

    Article  PubMed  PubMed Central  Google Scholar 

  • Cipriani, G., et al. (2020). Daily functioning and dementia. Dementia & Neuropsychologia [online], 14(2), 93–102. [Accessed 27 June 2021]. Available from: https://doi.org/10.1590/1980-57642020dn14-020001. Epub 12 June 2020. ISSN 1980–5764.

  • Crocker, T., Forster, A., Young, J., Brown, L., Ozer, S., Smith, J., Green, J., Hardy, J., Burns, E., Glidewell, E., & Greenwood, D. C. (2013). Physical rehabilitation for older people in long-term care. The Cochrane database of systematic reviews, (2), CD004294. https://doi.org/10.1002/14651858.CD004294.pub3

  • de Medeiros, M. M. D., Carletti, T. M., Magno, M. B., et al. (2020). A institucionalização influencia a qualidade de vida dos idosos? Uma revisão sistemática e meta-análise. BMC Geriatrics, 20, 44. https://doi.org/10.1186/s12877-020-1452-0

    Article  PubMed  PubMed Central  Google Scholar 

  • de Souto Barreto, P., Cesari, M., Denormandie, P., Armaingaud, D., Vellas, B., & Rolland, Y. (2017). Exercise or Social Intervention for Nursing Home Residents with Dementia: A Pilot Randomized, Controlled Trial. Journal of the American Geriatrics Society, 65(9), E123–E129. https://doi.org/10.1111/jgs.14947

    Article  PubMed  Google Scholar 

  • Eaker, E. D., Vierkant, R. A., & Mickel, S. F. (2002). Predictors of nursing home admission and/or death in incident Alzheimer’s disease and other dementia cases compared to controls: A population-based study. Journal of Clinical Epidemiology, 55(5), 462–468. https://doi.org/10.1016/s0895-4356(01)00498-x

    Article  PubMed  Google Scholar 

  • Edwards, N., Gardiner, M., Ritchie, D. M., Baldwin, K., & Sands, L. (2008). Effect of exercise on negative affect in residents in special care units with moderate to severe dementia. Alzheimer Disease and Associated Disorders, 22(4), 362–368. https://doi.org/10.1097/WAD.0b013e31818ecbbc

    Article  PubMed  Google Scholar 

  • Fleiner, T., Leucht, S., Förstl, H., Zijlstra, W., & Haussermann, P. (2017). Effects of Short-Term Exercise Interventions on Behavioral and Psychological Symptoms in Patients with Dementia: A Systematic Review. Journal of Alzheimer’s Disease: JAD, 55(4), 1583–1594. https://doi.org/10.3233/JAD-160683

    Article  PubMed  Google Scholar 

  • Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189–198. https://doi.org/10.1016/0022-3956(75)90026-6

  • Forbes, D., Forbes, S. C., Blake, C. M., Thiessen, E. J., & Forbes, S. (2015). Exercise programs for people with dementia. Cochrane Database of Systematic Reviews, (4), CD006489.

  • Guitar, N. A., Connelly, D. M., Nagamatsu, L. S., Orange, J. B., & Muir-Hunter, S. W. (2018). The effects of physical exercise on executive function in community-dwelling older adults living with Alzheimer’s-type dementia: A systematic review. Ageing Research Reviews, 47, 159–167. https://doi.org/10.1016/j.arr.2018.07.009

    Article  PubMed  Google Scholar 

  • Guyatt, G. H., Oxman, A. D., Kunz, R., Vist, G. E., Falck-Ytter, Y., Schünemann, H. J., & GRADE Working Group. (2008). What is “quality of evidence” and why is it important to clinicians? BMJ (clinical Research Ed.), 336(7651), 995–998. https://doi.org/10.1136/bmj.39490.551019.BE

    Article  Google Scholar 

  • Henskens, M., Nauta, I. M., van Eekeren, M., & Scherder, E. (2018a). Effects of Physical Activity in Nursing Home Residents with Dementia: A Randomized Controlled Trial. Dementia and Geriatric Cognitive Disorders, 46(1–2), 60–80. https://doi.org/10.1159/000491818

    Article  PubMed  Google Scholar 

  • Henskens, M., Nauta, I. M., Drost, K. T., & Scherder, E. J. (2018b). The effects of movement stimulation on activities of daily living performance and quality of life in nursing home residents with dementia: A randomized controlled trial. Clinical Interventions in Aging, 13, 805–817. https://doi.org/10.2147/CIA.S160031

    Article  PubMed  PubMed Central  Google Scholar 

  • Lam, F. M., Huang, M. Z., Liao, L. R., Chung, R. C., Kwok, T. C., & Pang, M. Y. (2018). Physical exercise improves strength, balance, mobility, and endurance in people with cognitive impairment and dementia: A systematic review. Journal of Physiotherapy, 64(1), 4–15. https://doi.org/10.1016/j.jphys.2017.12.001

    Article  PubMed  Google Scholar 

  • Morris, C., Heyman, A., Mohs, R. C., et al. (1993). The consortium toestablish a registry for Alzheimer’s disease. Part IV. Rates of cognitive change in the longitudinalassessment of probable Alzheimer’s disease. Neurology, 43, 2457–65.

    Article  CAS  PubMed  Google Scholar 

  • Joling, K. J., Janssen, O., Francke, A. L., Verheij, R. A., Lissenberg-Witte, B. I., Visser, P. J., & van Hout, H. (2020). Time from diagnosis to institutionalization and death in people with dementia. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 16(4), 662–671. https://doi.org/10.1002/alz.12063

    Article  Google Scholar 

  • Lautenschlager, N. T., Cox, K., & Kurz, A. F. (2010). Physical activity and mild cognitive impairment and Alzheimer’s disease. Current Neurology and Neuroscience Reports, 10(5), 352–358. https://doi.org/10.1007/s11910-010-0121-7

    Article  PubMed  Google Scholar 

  • Littbrand, H., Rosendahl, E., Lindelöf, N., Lundin-Olsson, L., Gustafson, Y., & Nyberg, L. (2006). A high-intensity functional weight-bearing exercise program for older people dependent in activities of daily living and living in residential care facilities: Evaluation of the applicability with focus on cognitive function. Physical Therapy, 86(4), 489–498.

    Article  PubMed  Google Scholar 

  • Liu, I. T., Lee, W. J., Lin, S. Y., Chang, S. T., Kao, C. L., & Cheng, Y. Y. (2020). Therapeutic Effects of Exercise Training on Elderly Patients with Dementia: A Randomized Controlled Trial. Archives of Physical Medicine and Rehabilitation, 101(5), 762–769. https://doi.org/10.1016/j.apmr.2020.01.012

    Article  PubMed  Google Scholar 

  • Lobo, A., Launer, L. J., Fratiglioni, L., Andersen, K., Di Carlo, A., Breteler, M. M., Copeland, J. R., Dartigues, J. F., Jagger, C., Martinez-Lage, J., Soininen, H., & Hofman, A. (2000). Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology, 54(11 Suppl 5), S4−S9.

  • Maltais, M., Rolland, Y., Vellas, B., Haÿ, P. E., Armaingaud, D., Cestac, P., Rouch, L., Cesari, M., & de Souto Barreto, P. (2019). Effect of Exercise on Behavioral Symptoms and Pain in Patients with Dementia Living in Nursing Homes. American Journal of Alzheimer’s Disease and Other Dementias, 34(2), 89–94. https://doi.org/10.1177/1533317518803773

    Article  PubMed  Google Scholar 

  • Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., McGuinness, L. A., Stewart, L. A., Thomas, J., Tricco, A. C., Welch, V. A., Whiting, P., & Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ (Clinical research ed.), 372(71). https://doi.org/10.1136/bmj.n71

  • Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., George, S. M., & Olson, R. D. (2018). The Physical Activity Guidelines for Americans. JAMA, 320(19), 2020–2028. https://doi.org/10.1001/jama.2018.14854

    Article  PubMed  PubMed Central  Google Scholar 

  • Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. (2016). BMJ (Clinical research ed.), 354, i4086. https://doi.org/10.1136/bmj.i4086

  • Telenius, E. W., Engedal, K., & Bergland, A. (2015). Long-term effects of a 12 weeks high-intensity functional exercise program on physical function and mental health in nursing home residents with dementia: A single blinded randomized controlled trial. BMC Geriatrics, 15, 158. https://doi.org/10.1186/s12877-015-0151-8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Terwee, C. B., Bot, S. D., de Boer, M. R., van der Windt, D. A., Knol, D. L., Dekker, J., Bouter, L. M., & de Vet, H. C. (2007). Quality criteria were proposed for measurement properties of health status questionnaires. Journal of Clinical Epidemiology, 60(1), 34–42.

    Article  PubMed  Google Scholar 

  • Toots, A., Littbrand, H., Lindelöf, N., Wiklund, R., Holmberg, H., Nordström, P., Lundin-Olsson, L., Gustafson, Y., & Rosendahl, E. (2016). Effects of a High-Intensity Functional Exercise Program on Dependence in Activities of Daily Living and Balance in Older Adults with Dementia. Journal of the American Geriatrics Society, 64(1), 55–64. https://doi.org/10.1111/jgs.13880

    Article  PubMed  PubMed Central  Google Scholar 

  • Toots, A., Wiklund, R., Littbrand, H., Nordin, E., Nordström, P., Lundin-Olsson, L., Gustafson, Y., & Rosendahl, E. (2019). The Effects of Exercise on Falls in Older People with Dementia Living in Nursing Homes: A Randomized Controlled Trial. Journal of the American Medical Directors Association, 20(7), 835-842.e1. https://doi.org/10.1016/j.jamda.2018.10.009

    Article  PubMed  Google Scholar 

  • Yamato, T. P., Maher, C., Koes, B., & Moseley, A. (2017). The PEDro scale had acceptably high convergent validity, construct validity, and interrater reliability in evaluating methodological quality of pharmaceutical trials. Journal of Clinical Epidemiology, 86, 176–181. https://doi.org/10.1016/j.jclinepi.2017.03.002

    Article  PubMed  Google Scholar 

  • Watanabe, Helena Akemi Wada; Di Giovanni, Vera Maria. Instituições de Longa Permanência para Idosos (ILPI). BIS, Bol. Inst. Saúde (Impr.). São Paulo, n. 47, abril 2009. Disponível em http://periodicos.ses.sp.bvs.br/scielo.php?script=sci_arttext&pid=S1518-18122009000200018&lng=es&nrm=iso. Acesso em: 13 julho 2020.

  • World Health Organization (Who). Dementia. 21 de setembro de 2020. Disponível em: https://www.who.int/news-room/fact-sheets/detail/dementia. Acesso em: 11 novembro 2020.

Download references

Funding

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.

Author information

Authors and Affiliations

Authors

Contributions

The preparation of the material, collection, and design of the study and data analysis were carried out by Elenderjane Andrade de Oliveira¹, Ully Alexia Caproni Correa¹ and Leani Souza Maximo Pereira². The first draft of the manuscript was written by Elenderjane Andrade de Oliveira¹, Ully Alexia Caproni Correa¹ and Leani Souza Maximo Pereira², all authors commented on previous versions of the manuscript. Conceptualization, Methodology, Formal analysis, investigation and writing and original preparation of the draft were done by Elenderjane Andrade de Oliveira¹, Ully Alexia Caproni Correa¹, Daniele Sirineu Pereira², Marcella Guimaraes Assis³ and Leani Souza Maximo Pereira². Writing, proofreading and editing Natalia Reynaldo Sampaio¹. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Elenderjane Andrade de Oliveira.

Ethics declarations

Conflict of Interest

We have no conflict of interest to declare.

Informed Consent

None.

Ethical Treatment of Experimental Subjects (Animal and Human)

No experimental treatment was conducted on either human or animal subject in this study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

de Oliveira, E.A., Correa, U.A.C., Sampaio, N.R. et al. Physical Exercise on Physical and Cognitive Function in Institutionalized Older Adults with Dementia: A Systematic Review. Ageing Int (2024). https://doi.org/10.1007/s12126-023-09542-9

Download citation

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s12126-023-09542-9

Keywords

Navigation