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Epithelioid Sarcoma of the External Auditory Canal: An Uncommon Tumor at an Unusual Site and a Brief Overview of the Literature

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Abstract

We present a case (41 years old pregnant female) with epithelioid sarcoma arising in the left external auditory canal. On immunohistochemistry, the tumor cell diffusely expressed cytokeratins and showed patchy expression of ERG and CD34. The neoplastic cells demonstrated uniform loss of INI1-expression. Epithelioid sarcoma arising in the external auditory canal is rare. Awareness that ES may rarely arise at unusual sites is of critical importance in order to apply a broad enough panel in the immunohistochemical study, so a misdiagnosis of carcinoma can be avoided.

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Acknowledgements

The authors would like to thank Dr Christopher D.M. Fletcher (Professor of Pathology at Harvard Medical School, and Vice Chair of Anatomic Pathology at Brigham and Women’s Hospital) for his expert opinion on this case.

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  1. Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore

    Bingcheng Wu & Fredrik Petersson

  2. Department of Otolaryngology, National University Health System, Singapore, Singapore

    Joshua Kai Xun Tay & Woei Shyang Loh

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Wu, B., Tay, J.K.X., Loh, W.S. et al. Epithelioid Sarcoma of the External Auditory Canal: An Uncommon Tumor at an Unusual Site and a Brief Overview of the Literature. Head and Neck Pathol 15, 1328–1334 (2021). https://doi.org/10.1007/s12105-020-01275-4

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