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Intraoral Basal Cell Carcinoma of Soft Palate: A Diagnostic Dilemma and Review of Literature

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Basal cell carcinoma is the most common cancer worldwide. Most of basal cell carcinoma can be detected in the early stages and are generally well controlled with local resection. Despite the high incidence of BCC, intramucosal BCC is a very rare clinical entity. We hereby present a rare case report of pigmented BCC on soft palate and review the literature of this entity.

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References

  1. Wu S, Han J, Li WQ, Li T, Qureshi AA (2013) Basal-cell carcinoma incidence and associated risk factors in U.S. women and men. Am J Epidemiol 178:890–897

    Article  PubMed  PubMed Central  Google Scholar 

  2. Bath-Hextall F, Bong J, Perkins W, Williams H (2004) Interventions for basal cell carcinoma of the skin: systematic review. BMJ 329:705

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wadhera A, Fazio M, Bricca G, Stanton O (2006) Metastatic basal cell carcinoma: a case report and literature review. How accurate is our incidence data? Dermatol Online J 12(5):7

    PubMed  Google Scholar 

  4. Saint CF (1951) The embryology of the stomodeum and its bearing on the pathology of tumours of the tongue and the salivary glands. S Afr J Clin Sci 2:1–17

    CAS  PubMed  Google Scholar 

  5. Del Rosario RN, Barr RJ, Jensen JL, Cantos KA (2001) Basal cell carcinoma of the buccal mucosa. Am J Dermatopathol 23:203–205

    Article  PubMed  Google Scholar 

  6. Shumway BS, Kalmar JR, Allen CM, Rawal YB (2011) Basal cell carcinoma of the buccal mucosa in a patient with nevoid basal cell carcinoma syndrome. Int J Surg Pathol 19:348–354

    Article  PubMed  Google Scholar 

  7. Latza U, Niedobitek G, Schwarting R, Nekarda H, Stein H (1990) Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelial. J Clin Pathol 43:213–219

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Tellechea O, Reis JP, Domingues JC, Baptista AP (1993) Monoclonal antibody Ber EP4 distinguishes basal-cell carcinoma from squamous-cell carcinoma of the skin. Am J Dermatopathol 15:452–455

    Article  CAS  PubMed  Google Scholar 

  9. Yu L, Galan A, McNiff JM (2009) Caveats in BerEP4 staining to differentiate basal and squamous cell carcinoma. J Cutan Pathol 36:1074–1176

    Article  PubMed  Google Scholar 

  10. Winters R, Naud S, Evans MF, Trotman W, Kasznica P, Elhosseiny A (2008) Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. Head Neck Pathol 2:265–271

    Article  PubMed  PubMed Central  Google Scholar 

  11. el-Mofty SK, Gerard NO, Farish SE, Rodu B (1991) Peripheral ameloblastoma: a clinical and histologic study of 11 cases. J Oral Maxillofac Surg 49:970–974

    Article  CAS  PubMed  Google Scholar 

  12. Ide F, Mishima K, Miyazaki Y, Saito I, Kusama K (2009) Peripheral ameloblastoma in situ: an evidential fact of surface epithelium origin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:763–767

    Article  PubMed  Google Scholar 

  13. Beer TW, Shepherd P, Theaker JM (2000) Ber EP4 and epithelial membrane antigen aid distinction of basal cell, squamous cell and basosquamous carcinomas of the skin. Histopathology 37:218–223

    Article  CAS  PubMed  Google Scholar 

  14. Fan YS, Carr RA, Sanders DS, Smith AP, Lazar AJ, Calonje E (2007) Characteristic Ber-EP4 and EMA expression in sebaceoma is immunohistochemically distinct from basal cell carcinoma. Histopathology 51:80–86

    Article  CAS  PubMed  Google Scholar 

  15. Weedon D (2010) Tumours of the epidermis. In: Weedon D (ed) Churchill Livingstone Elsevier, Edinburgh, pp 685–686

  16. Barnhill RL (2004) Tumors of the epidermis. In: Crowson AN (ed) McGraw-Hill, New York, pp 599–608

  17. Stanley HR Jr, Krogh HW (1959) Peripheral ameloblastoma; report of a case. Oral Surg Oral Med Oral Pathol 12:760–765

    Article  PubMed  Google Scholar 

  18. Lawson BF, Griffin JW, Waldron CA (1967) Basal-cell carcinoma of the gingiva. Report of a case. Oral Surg Oral Med Oral Pathol 24:648–653

    Article  CAS  PubMed  Google Scholar 

  19. Mori M, Morimoto Y, Yoshimura Y, Kawamura H (1968) Enzymatic histochemical demonstration of basal-cell carcinoma in the oral cavity. Oral Surg Oral Med Oral Pathol 25:746–755

    Article  CAS  PubMed  Google Scholar 

  20. Peters RA, Gingrass RP, Reyes CN, Hintz CS (1972) Basal cell carcinoma of the oral cavity: report of case. J Oral Surg 30:63–66

    CAS  PubMed  Google Scholar 

  21. Liroff KP, Zeff S (1972) Basal cell carcinoma of the palatal mucosa. J Oral Surg 30:730–733

    CAS  PubMed  Google Scholar 

  22. Samit AM (1978) Intraoral basal cell carcinoma. J Surg Oncol 10:27–32

    Article  CAS  PubMed  Google Scholar 

  23. Simpson HE (1974) Basal-cell carcinoma and peripheral ameloblastoma. Oral Surg Oral Med Oral Pathol 38:233–240

    Article  CAS  PubMed  Google Scholar 

  24. Thoma KH, Goldman HM (1960) Oral pathology. Edited by St. Louis, MO, CV Mosby

  25. Williamson JJ, Cohney BC, Henderson BM (1967) Basal cell carcinoma of the mandibular gingiva. Arch Dermatol 95:76–80

    Article  CAS  PubMed  Google Scholar 

  26. Keen RR, Elzay RP (1964) Basal cell carcinoma from mucosal surface of lower lip: report of case. J Oral Surg Anesth Hosp Dent Serv 22:453–455

    CAS  PubMed  Google Scholar 

  27. Blinder D, Taicher S (1992) Metastatic basal cell carcinoma presenting in the oral cavity and auditory meatus. A case report and review of literature. Int J Oral Maxillofac Surg 21:31–34

    Article  CAS  PubMed  Google Scholar 

  28. Koutlas IG, Koch CA, Vickers RA, Brouwers FM, Vortmeyer AO (2009) An unusual ostensible example of intraoral basal cell carcinoma. J Cutan Pathol 36:464–470

    Article  PubMed  Google Scholar 

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MS, KKL, AC, RC made and reviewed the manuscript and SS, GS, AJ reviewed the manuscript.

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Correspondence to Manish Sahni.

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Sahni, M., Lakhera, K.K., Chatterjee, A. et al. Intraoral Basal Cell Carcinoma of Soft Palate: A Diagnostic Dilemma and Review of Literature. Indian J Otolaryngol Head Neck Surg 76, 2205–2211 (2024). https://doi.org/10.1007/s12070-023-04452-3

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