Skip to main content
Log in

Intracranial Remote Metastasis from Adenoid Cystic Cancer of Parotid Gland: Case Report and Review of Literature

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Adenoid cystic carcinoma is rare, locally aggressive salivary gland tumor. It has indolent course, multiple local recurrences and delayed distant metastasis in lung, bone, liver and soft tissues which are detected up to a maximum of 5.5 years after local-regional resection of the primary tumor. Intracranial remote metastasis of ACCs is extremely rare, and very few cases have been reported in the literature. Here we report a rare case of intracranial remote metastasis of ACC of the parotid gland developed after 15 years of primary curative surgery, emphasizing long term follow up on these cases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. De Berardinis R, Viziano A, Micarelli A, Alessandrini M, Bruno E (2018) Adenoid cystic carcinoma of head and neck. Am J Otolaryngol Head Neck Surg 1(2):1010

    Google Scholar 

  2. Ramakrishna R, Raza SM, Kupferman M, Hanna E, DeMonte F (2016) Adenoid cystic carcinoma of the skull base: results with an aggressive multidisciplinary approach. J Neurosurg 124(1):115–121

    Article  Google Scholar 

  3. Chaturvedi J, Konar SK, Jethwani D, Srinivas D, Mahadevan A (2017) Metastatic intracranial adenoid cystic carcinoma with unknown primary: case report and review of literature. J Neurosci Rural Pract 8(2):274–276

    Article  Google Scholar 

  4. Pires A, Vieira C, Jácome M, Moreira D, Arantes M (2020) Pachymeningeal carcinomatosis: an unusual location of metastization of adenoid cystic carcinoma. Braz J Otorhinolaryngol. https://doi.org/10.1016/j.bjorl.2020.10.013

    Article  Google Scholar 

  5. Bozkurt G, Jayan G, Mahmutoglu AS (2020) Adenoid cystic carcinoma of the parotid metastasising to the dura fifteen years post primary resection: a case report. North Clin Istanb 7(3):294–297

    Google Scholar 

  6. Kawamata T, Harashima S, Kubo O, Hori T (2006) Intrasellar remote metastasis from adenoid cystic carcinoma of parotid gland: case report. Endocr J 53(5):659–663. https://doi.org/10.1507/endocrj.k05-146

    Article  Google Scholar 

  7. Adachi K, Yoshida K, Ueda R, Kawase T (2006) Adenoid cystic carcinoma of the cavernous region. Case Report Neurol Med Chir (Tokyo) 46(7):358–360. https://doi.org/10.2176/nmc.46.358

    Article  Google Scholar 

  8. Kumar V, Nair R, Upadhyaya S, Nayal B, Shetty A (2015) Extradural spinal metastasis of adenoid cystic carcinoma (ACC): a case report. J Clin Diagn Res 9(1):XD09-XD10. https://doi.org/10.7860/JCDR/2015/10644.5498

    Article  Google Scholar 

  9. Venteicher AS, Walcott BP, Sheth SA, Snuderl M, Patel AP, Curry WT, Nahed BV (2013) Clinical features of brain metastasis from salivary gland tumors. J Clin Neurosci 20(11):1533–1537. https://doi.org/10.1016/j.jocn.2012.11.024

    Article  Google Scholar 

  10. Gelber ND, Ragland RL, Knorr RL, Smith TW, Stone BB (1992) Intracranial metastatic adenoid cystic carcinoma: presumed hematogenous spread from a primary tumor in the parotid gland. AJR 158:1163–1164

    Article  CAS  Google Scholar 

  11. Hammoud MA, Hassenbusch SJ, Fuller GN et al (1996) Multiple brain metastases: a rare manifestation of adenoid cystic carcinoma of the parotid gland. J Neuro-Oncol 27:61–64. https://doi.org/10.1007/BF00146085

    Article  CAS  Google Scholar 

  12. Kazumoto K, Hayase N, Kurosumi M, Kishi K, Uki J, Takeda F (1998) Multiple brain metastases from adenoid cystic carcinoma of the parotid gland. Case report and review of the literature. Surg Neurol 50(5):475–479. https://doi.org/10.1016/s0090-3019(97)00341-8

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V. B. Shivkumar.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Atram, M.A., Shivkumar, V.B. & Gangane, N.M. Intracranial Remote Metastasis from Adenoid Cystic Cancer of Parotid Gland: Case Report and Review of Literature. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5949–5953 (2022). https://doi.org/10.1007/s12070-021-02594-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-021-02594-w

Keywords

Navigation