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The Association Between Dietary Magnesium Intake and Pulmonary Function: Recent Fndings from NHANES 2007–2012

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Abstract

This article aims to study the correlation between dietary magnesium intake and pulmonary function, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database. This cross-sectional study examined representative samples of adults from the USA (n = 818; NHANES 2007–2012) to explore the correlation between magnesium intake and pulmonary function. We obtained the average magnesium intake over 2 days, as well as measured pulmonary function parameters, including forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), FEV1/FVC, peak expiratory flow rate (PEF), and forced expiratory flow between 25 and 75% of FVC (FEF25-75%). Weighted multivariable linear regression was used to investigate the relationship between magnesium intake and pulmonary function. Additionally, subgroup analyses, interaction tests, and sensitivity analyses were conducted. Weighted multiple linear regression models revealed a significant positive correlation between magnesium and pulmonary function, even after adjusting for all included confounding variables. When we categorized magnesium intake into tertiles, we found that participants in the highest tertile of magnesium intake had significantly higher values for FVC (β: 898.54, 95%CI: 211.82–1585.25), FEV1 (β: 858.16, 95%CI: 212.41–1503.91), FEV1/FVC (β: 0.024, 95%CI: 0.004–0.044), PEF (β: 1324.52, 95%CI: 481.71–2167.33), and FEF25-75% (β: 831.39, 95%CI: 84.93–1577.84). Upon stratifying the data by age and sex, it was observed that this positive correlation was particularly pronounced among men aged 40–79. At the same time, the stability of the results was further confirmed by sensitivity analyses. This study suggested that dietary magnesium intake may improve pulmonary function.

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Data Availability

Publicly available datasets were analyzed in this study. This data can be found here: https://www.cdc.gov/nchs/nhanes.

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Author notes

  1. Mo-Yao Tan and Jian-Tao Wang contributed equally to the article

Authors and Affiliations

  1. Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China

    Mo-Yao Tan, Jian-Tao Wang, Gao-Peng Wang & Si-Xuan Zhu

  2. Chengdu Integrated TCM and Western Medicine Hospital, Chengdu, Sichuan, China

    Xiang-Long Zhai

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Contributions

Mo-Yao Tan, Jian-Tao Wang, and Xiang-Long Zhai conceived and designed the study. Mo-Yao Tan, Jian-Tao Wang, and Xiang-Long Zhai conducted data collection, data analysis, and data interpretation. Mo-Yao Tan, Si-Xuan Zhu, and Gao-Peng Wang contributed to literature checks and data visualization. Mo-Yao Tan drafted the initial manuscript and all authors made critical revisions of the manuscript. Mo-Yao Tan, Si-Xuan Zhu, and Gao-Peng Wang verified the underlying study data. All authors read the manuscript and approved the final draft. All authors confirm that they had full access to all the data in the study and accept responsibility to submit for publication.

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Correspondence to Xiang-Long Zhai.

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Tan, MY., Wang, JT., Wang, GP. et al. The Association Between Dietary Magnesium Intake and Pulmonary Function: Recent Fndings from NHANES 2007–2012. Biol Trace Elem Res (2024). https://doi.org/10.1007/s12011-024-04061-3

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