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Clinical Utility of [18F]FDG-PET /CT in Pericardial Disease

  • Pericardial Disease (AL Klein and CL Jellis, Section Editors)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Identification of the etiology of pericardial disease is challenging because the accessibility to pericardial fluid and tissue is limited and there is a relatively low yield of fluid and tissue analysis. Pericardial disease is associated with various systemic diseases and is frequently a first manifestation of other systemic diseases. Detecting the cause of pericarditis and minimizing the subsequent inflammatory process can possibly prevent long-term complications.

Purpose of Review

To review the clinical utility of [18F]-2-deoxy-2-fluoro-D-glucose positron emission tomography/computed tomography ([18F]FDG-PET/CT) in the diagnosis and treatment of pericardial disease.

Recent Findings

[18F]FDG-PET/CT can visualize the hypermetabolic tissues of both malignancy and inflammation. Distribution of [18F]FDG-PET/CT uptake can provide information for neoplastic disease. If malignancy is ruled out, high uptake of pericardium is associated with active inflammation of the pericardium, and thus response to anti-inflammatory agents can also be predicted with [18F]FDG-PET/CT imaging.

Summary

[18F]FDG-PET/CT can be helpful for diagnosing and establishing prognosis and for planning for anti-inflammatory treatment in pericardial disease.

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Authors and Affiliations

  1. Division of Cardiology, Department of Medicine, Samsung Medical Center, Heart Vascular and Stroke Institute Imaging Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea

    Min-Sun Kim, Eun-Kyung Kim & Sung-A Chang

  2. Department of Nuclear Medicine and Molecular Imaging, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

    Joon Young Choi

  3. Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA

    Jae K. Oh

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  1. Min-Sun Kim
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  5. Sung-A Chang
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Correspondence to Sung-A Chang.

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Min-Sun Kim, Eun-Kyung Kim, Joon Young Choi, Jae K. Oh, and Sung-A Chang declare that they have no conflict of interest.

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All reported studies/experiments with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines).

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This article is part of the Topical Collection on Pericardial Disease

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Kim, MS., Kim, EK., Choi, J.Y. et al. Clinical Utility of [18F]FDG-PET /CT in Pericardial Disease. Curr Cardiol Rep 21, 107 (2019). https://doi.org/10.1007/s11886-019-1193-x

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  • DOI: https://doi.org/10.1007/s11886-019-1193-x

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