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Recent Advances in Coronary Computed Tomography Angiogram: The Ultimate Tool for Coronary Artery Disease

  • Coronary Heart Disease (Virani and M. Al Rifai, Section Editor)
  • Published:
Current Atherosclerosis Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

The emerging technologies in multidetector computed tomography scanners gave the ability to image coronary arteries in a single heartbeat, at a higher quality, and low radiation dose. Furthermore, incorporating artificial intelligence and machine learning into image processing and interpretation have extended the use for coronary computed tomography angiogram (CCTA) and its applications. In this review, we will explore the recent evidence and advances supporting CCTA to become the ultimate tool for coronary artery disease.

Recent Findings

Results from the EVINCI, ISCHEMIA, SCOT-HEART, and PROMISE showed that CCTA is better in patients’ risk stratification and in detecting subclinical atherosclerosis, resulting in earlier interventions and lesser events. Additionally, CCTA gave us a closer look on atherosclerotic disease by identifying different type of plaque and their clinical significance. Furthermore, FFRCT is a notable example of incorporating artificial intelligence into CCTA. This technology helped us to accurately and non-invasively identify flow limiting lesions, guiding revascularization.

Summary

As a result of the recent evidence, CCTA have made its way into the chest pain guidelines all over the world. Moreover, CCTA have the potential to revolutionize our understanding and standards in screening, preventing, and managing heart disease.

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Funding

Dr. Budoff reports grants from National Institutes of health, grants from General Electric, during the conduct of the study.

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Authors and Affiliations

  1. Department of Cardiology, Lundquist Institute at Harbor UCLA Medical Center, 1209 W 220th St, Torrance, CA, 90502, USA

    Luay Alalawi & Matthew J. Budoff

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  1. Luay Alalawi
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Correspondence to Matthew J. Budoff.

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Alalawi, L., Budoff, M.J. Recent Advances in Coronary Computed Tomography Angiogram: The Ultimate Tool for Coronary Artery Disease. Curr Atheroscler Rep 24, 557–562 (2022). https://doi.org/10.1007/s11883-022-01029-3

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