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Different application procedures of Nd:YAG laser as an adjunct to scaling and root planning in smokers with stage III grade C periodontitis: a single-blind, randomized controlled trial

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Abstract

Background

The aim of the present study was to evaluate whether different Nd:YAG laser applications as an adjunct to scaling and root planning (SRP) improve the healing response to periodontal therapy in smokers with periodontitis.

Methods

This clinical trial included eighty systemically healthy smokers with periodontitis. Patients were randomly allocated to a treatment group: SRP alone (group 1), SRP+low-level laser therapy (LLLT) with Nd:YAG laser (group 2), SRP+pocket debridement with ND:YAG laser (group 3), and SRP+combined pocket debridement and LLLT with Nd:YAG laser (group 4). Gingival index (GI), plaque index (PI), bleeding on probing (%), probing depth (PD), and clinical attachment level (CAL) were recorded, and gingival crevicular fluid (GCF) samples for metalloproteinase-8 (MMP-8) levels were collected at baseline, 1 month and 3 months after treatment.

Results

There were no significant differences between the treatment groups for the GI, PI, and BOP (%) parameters and MMP-8 levels at any time points (p > 0.05). For moderately deep pockets, PD and CAL reductions were significantly greater in all test groups compared to group 1 (p ˂ 0.05). For deep pockets, these reductions were significantly greater in group 2 and group 4 compared to group 1 (p ˂ 0.05). PD and CAL reductions were generally similar between test groups (p > 0.05) except PD reduction between baseline and 3 months in deep pockets (p ˂ 0.05).

Conclusions

The findings of this clinical trial suggest that Nd:YAG laser applications may be beneficial on the healing response of smokers to non-surgical therapy compared to SRP alone.

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Acknowledgements

We would like to thank Assoc. Prof. Ferhan Elmalı for his statistical assistance.

Funding

This study was funded by The Scientific Research Coordination Office of Izmir Katip Çelebi University (2017-TDU-DİŞF-0034).

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Authors and Affiliations

  1. Department of Periodontology, Faculty of Dentistry, Izmir Katip Çelebi University, Izmir, Turkey

    Alparslan Ezber, İsmail Taşdemir & Mehmet Sağlam

  2. Department of Periodontology, Faculty of Dentistry, Karamanoğlu Mehmetbey University, Karaman, Turkey

    İsmail Taşdemir

  3. Department of Medical Biochemistry, School of Medicine, Izmir Katip Çelebi University, Izmir, Turkey

    Huriye Erbak Yılmaz & Figen Narin

  4. Dokuz Eylül University Izmir Biomedicine and Genome Center, Izmir, Turkey

    Huriye Erbak Yılmaz

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  1. Alparslan Ezber
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  5. Mehmet Sağlam
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Correspondence to Mehmet Sağlam.

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Ethics approval

All procedures in this study were approved by the Ethics Committee of Izmir Katip Celebi University for human subjects (2017/106) and also the Republic of Turkey Ministry of Health, Turkey Pharmaceuticals and Medical Devices Agency (No: 71146310-511.06-E.213417 Subject: 2017-102). Clinical trial serial number: TCTR20190926001.

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Ezber, A., Taşdemir, İ., Yılmaz, H.E. et al. Different application procedures of Nd:YAG laser as an adjunct to scaling and root planning in smokers with stage III grade C periodontitis: a single-blind, randomized controlled trial. Ir J Med Sci 192, 457–466 (2023). https://doi.org/10.1007/s11845-022-02940-z

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