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Clinical observation of pediatric Tuina plus oral Chinese medication for pediatric anorexia due to spleen failing in transportation

小儿推拿加中药口服治疗脾失健运型儿童厌食的临床观察

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Abstract

Objective

To observe the clinical efficacy of pediatric Tuina (Chinese therapeutic massage) plus oral administration of Chinese medication for pediatric anorexia due to spleen failing in transportation.

Methods

A total of 94 children with anorexia due to spleen failing in transportation were randomized into an observation group and a control group by the random number table method at a ratio of 1:1, with 47 cases in each group. The control group was treated with modified Bu Huan Jin Zheng Qi San, and the observation group was treated with additional Tuina manipulation of Yun Shui Ru Tu based on the treatment in the control group. After 4 weeks of treatment, the clinical efficacy of the two groups was observed, and the traditional Chinese medicine (TCM) symptom score, serum leptin, neuropeptide Y, and serum zinc and calcium levels were compared.

Results

After 4 weeks of treatment, the total effective rate of the observation group was 87.2%, and that of the control group was 74.5%. The difference between the two groups was statistically significant P<0.05). After treatment, the TCM symptom scores in both groups decreased significantly (P<0.05), and the scores in the observation group were lower than those in the control group (P<0.05). After treatment, the serum leptin level in both groups decreased, and the level in the observation group was lower than that in the control group (P<0.05). The serum neuropeptide Y, zinc, and calcium levels in both groups increased after treatment, and the levels in the observation group were higher than those in the control group (P<0.05).

Conclusion

Tuina manipulation of Yun Shui Ru Tu plus oral administration of Chinese medication is significantly effective in treating pediatric anorexia due to spleen failing in transportation, which can improve the appetite of children and improve the symptoms of anorexia, and the curative effect is better than that of oral administration of Chinese medication alone.

【摘要】

目的

观察小儿推拿加中药口服治疗脾失健运型儿童厌食的临床疗效。

方法

将94例脾失健运型厌食患儿根 据随机数字表法按1:1分为观察组与对照组, 每组47例。对照组给予不换金正气散加减治疗, 观察组在对照组治疗基 础上加用运水入土推拿手法治疗。治疗4周后, 观察两组临床疗效, 比较中医症状评分、血清瘦素、神经肽Y及血锌、 血钙水平变化。

结果

治疗4周后, 观察组总有效率为87.2%, 对照组总有效率为74.5%, 两组差异具有统计学意义 (P<0.05)。治疗后两组中医症状评分均较治疗前显著下降(P<0.05), 且观察组评分低于对照组(P<0.05)。治疗后两组血 清瘦素水平较治疗前下降, 且观察组低于对照组(P<0.05)。治疗后两组血清神经肽Y、血锌和血钙水平均较治疗前升 高, 且观察组高于对照组(P<0.05)。

结论

运水入土推拿手法结合中药口服治疗脾失健运型厌食患儿疗效显著, 可提 高患儿食欲, 改善患儿厌食症状, 疗效优于单独中药口服。

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References

  1. LI H W, LUO X Y. Effects of Saccharomyces boulardii combined with zinc gluconate in treatment of child anorexia and its influence on blood trace elements. Zhonghua Zaihai Jiuyuan Yixue, 2020, 8(7): 384–386, 394.

    Google Scholar 

  2. LI Y. Observation on treating infantile anorexia with the Yihuang powder plus calcium zinc gluconate oral solution. Zhongyi Linchuang Yanjiu, 2020, 12(1): 69–72.

    Google Scholar 

  3. HUANG Q, LING Z J, HUANG Y W, ZHANG M H, YANG Y, LUO K Y. Observation on the effect of lysine zinc gluconate granules in the treatment of anorexia in children with zinc deficiency. Linchuang Heli Yongyao Zazhi, 2020, 13(32): 107–108.

    Google Scholar 

  4. XING K, CHEN J S, ZHANG L L, WANG J, LI Z H. Clinical study on the treatment of anorexia in children by Tui Na therapy combined with self-made Jianpi-Tiaogan decoction. Guoji Zhongyi Zhongyao Zazhi, 2020, 42(11): 1083–1087.

    Google Scholar 

  5. ZHU H, DING P. Clinical efficacy and safety observation of Yinshao Liujun decoction combined with acupuncture at Sifeng (EX-UE10) in the treatment of anorexia in children due to spleen deficiency. Sichuan Zhongyi, 2020, 38(11): 82–84.

    Google Scholar 

  6. YU J Q. The research progress of massage and acupuncture in the treatment of infantile anorexia. Zhongguo Yiliao Qixie Xinxi, 2020, 26(20): 26, 52.

    Google Scholar 

  7. DU Y Y, YU N N, CUI H L. Clinical observation of embedding needle combined with chiropractic therapy on infantile anorexia. Hubei Zhongyi Zazhi, 2021, 43(1): 21–24.

    Google Scholar 

  8. FAN Y L, CHEN J J. Clinical study on FENG’s chiropractic technique combined with modified Wuwei Yigong powder in treatment of infantile anorexia of Qi deficiency syndrome of spleen and stomach. Liaoning Zhongyi Zazhi, 2021, 48(1): 131–133.

    Google Scholar 

  9. HUA J, SUN G M. Clinical observation on 35 cases of pediatric anorexia due to disharmony between Ying and Wei treated by formula granules for harmonizing Ying and Wei. Zhejiang Zhongyi Zazhi, 2020, 55(10): 768.

    Google Scholar 

  10. WANG Y, ZHONG D D, JI X H, CHENG Y B, GAO X D, ZHENG Y M, ZHAO L, LI K W. Multi-center randomized double-blind controlled study on children’s anorexia (spleen-stomach disharmony) treated with child compound endothelium corneum. Zhongguo Zhongyao Zazhi, 2021, 46(9): 2298–2300.

    PubMed  Google Scholar 

  11. State Administration of Traditional Chinese Medicine. Criteria of Diagnosis and Therapeutic Effects of Diseases and Syndromes in Traditional Chinese Medicine. Nanjing: Nanjing University Press, 1994: 291.

    Google Scholar 

  12. WANG S C. Pediatrics of Chinese Medicine. Beijing: China Press of Traditional Chinese Medicine, 2012: 135.

    Google Scholar 

  13. KONG X L, XU T H, HU S Y, LIU H, WANG H W, LI Z Y, XU F. Evaluation of reliability, validity and responsiveness of clinical efficacy scale of traditional Chinese medicine syndromes of infantile anorexia (feeding disorder). Zhongyi Zazhi, 2015, 56(9): 753–758.

    Google Scholar 

  14. HUANG M, WANG P L, NAN N, FAN Y H. The understanding and treatment status of Western medicine for functional dyspepsia in children. Zhongyi Linchuang Yanjiu, 2019, 11(36): 19–21.

    Google Scholar 

  15. WANG H Y. Observation on the curative effect of Shenqu Xiaoshi oral liquid in the treatment of functional dyspepsia in children. Beifang Yaoxue, 2019, 16(10): 70–71.

    Google Scholar 

  16. LIU J P, GUI H Y, LIAO Q H. Study on compound digestive enzyme combined with probiotics in the treatment of functional dyspepsia in children. Shiyong Zhongxiyi Jiehe Linchuang, 2019, 19(8): 96–97.

    Google Scholar 

  17. MANINI M L, CAMILLERI M. How does one choose the appropriate pharmacotherapy for pediatric patients with functional dyspepsia?. Expert Opin Pharmacother, 2019, 20(16): 1921–1924.

    Article  PubMed  PubMed Central  Google Scholar 

  18. XIE H, CAO Q L, CHEN W. Observation of the effect of domperidone tablets combined with standard triple therapy in the treatment of children with Hp infection complicated with functional dyspepsia. Linchuang Yixue Gongcheng, 2020, 27(7): 917–918.

    Google Scholar 

  19. LI W, GENG X R, HE L D, WU C X. The clinical value of three-dimensional ultrasound volume analysis software in evaluating gastric emptying function in children with functional dyspepsia. Zhongguo Jiceng Yixue, 2019, 25(14): 1716–1718.

    Google Scholar 

  20. GONG L M, ZHU L K, HU G H, PAN Y R. Clinical efficacy on Chaihu Shugansan combined with Saccharomyces boulardii in treatment of functional dyspepsia in children. Zhongguo Shiyan Fangjixue Zazhi, 2020, 26(11): 136–141.

    Google Scholar 

  21. LIU Z Q. Etiological analysis and related treatment study of functional dyspepsia in children. Zhongxiyi Jiehe Xinxueguanbing Dianzi Zazhi, 2020, 8(35): 184–185.

    Google Scholar 

  22. LOWKE M, BELL N, GARCIA M. Fibroblast growth factor 2 differentially influences leptin gene expression in dispersed adipose tissue cell cultures. FASEB J, 2021, 35(S1): 419.

    Article  Google Scholar 

  23. GALUSCA B, PRÉVOST G, GERMAIN N, DUBUC I, LING Y, ANOUAR Y, ESTOUR B, CHARTREL N. Neuropeptide Y and α-MSH circadian levels in two populations with low body weight: anorexia nervosa and constitutional thinness. PLoS One, 2015, 10(3): e0122040.

    Article  PubMed  PubMed Central  Google Scholar 

  24. SUN W L, ZHANG S. The efficacy of Huaji tablets and Erpixing granules in the treatment of anorexia in children and its influence on clinical symptoms, serum levels of appetite-stimulating hormone/leptin and neuropeptide Y. Shoudu Shipin Yu Yiyao, 2019, 26(19): 67.

    Google Scholar 

  25. ZHOU J C, CHEN J H, ZHONG Y Q, DENG M Y, HU Z D, ZHOU J H. Correlational study between TCM syndrome of anorexia and trace element & helicobacter pylori. Zhonghua Zhongyiyao Xuekan, 2013, 31(3): 613–614.

    CAS  Google Scholar 

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Acknowledgments

There was no project fund support for this study.

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Authors and Affiliations

  1. Jimo District Qingdao Hospital of Traditional Chinese Medicine, Shandong, 266200, China

    Tao Xie  (解涛), Hua Jiang  (江华) & Chengyan Zhang  (张成燕)

Authors
  1. Tao Xie  (解涛)
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  2. Hua Jiang  (江华)
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  3. Chengyan Zhang  (张成燕)
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Corresponding author

Correspondence to Tao Xie  (解涛).

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Author

XIE Tao, bachelor, attending physician.

Conflict of Interest

There is no potential conflict of interest in this article.

Statement of Informed Consent

Informed consent was obtained from the guardians of the recruited children in this study.

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Xie, T., Jiang, H. & Zhang, C. Clinical observation of pediatric Tuina plus oral Chinese medication for pediatric anorexia due to spleen failing in transportation. J. Acupunct. Tuina. Sci. 20, 119–125 (2022). https://doi.org/10.1007/s11726-022-1303-y

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  • DOI: https://doi.org/10.1007/s11726-022-1303-y

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