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Short-Term Changes on Body Composition and Bone Mass After One-Anastomosis Gastric Bypass: a Prospective Observational Study

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Abstract

Purpose

Bariatric surgery generates a large weight loss. It is considered a successful surgery when 50% of the excess weight loss is reached. However, this measure does not include some variables that may have a direct impact on a patient’s health, such as fat-free mass (FFM) or bone mass. Therefore, the aim of this study is to evaluate body composition and bone mass in patients undergoing one-anastomosis gastric bypass (OAGB).

Methods

A prospective observational study was performed in patients undergoing OAGB. Body composition and bone mass were evaluated by bioelectrical impedance analysis at baseline (1 day prior to surgery), at 6 and 12 months after surgery.

Results

A total of 94 patients (67% females and 33% males) were included in the study. The excess BMI loss at 6 and 12 months after surgery was 97.9 ± 20.1% and 110.2 ± 30.5% respectively. The FFM showed a reduction of 6.6 ± 4.8 kg (p < 0.01) 6 months after surgery and of 7.9 ± 4.9 kg (p < 0.01) at 12 months, meaning a decrease of 10.5 ± 7.3% and a 12.9 ± 6.6% respectively. The bone mass decrease was 10.1 ± 6.9% (p < 0.01) and 12.9 ± 6.5% (p < 0.01) at 12 months after OAGB.

Conclusions

OAGB obtains a relevant weight loss in patients with morbid obesity, mainly, due to fat mass reductions. However, this procedure also provokes FFM and bone mass decreases, especially in females, but not significantly greater than other restrictive or mixed procedures.

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Authors and Affiliations

  1. Laboratory of Training Analysis and Optimization, Sports Research Center, Miguel Hernández University, Alicante, Spain

    Artur Marc-Hernández

  2. Department of Health Sciences, Universidad Alfonso X, Villanueva de la Cañada, 28691, Madrid, Spain

    Jaime Ruiz-Tovar

  3. Nursing Faculty, Universidad de Valladolid, Valladolid, Spain

    Jose M. Jimenez, Maria Lopez, Maria J. Cao & Maria J. Castro

  4. Centre of Excellence for the Study and Treatment of Obesity and Diabetes, Valladolid, Spain

    Miguel A. Carbajo

Authors
  1. Artur Marc-Hernández
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  2. Jaime Ruiz-Tovar
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  3. Jose M. Jimenez
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  4. Miguel A. Carbajo
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  5. Maria Lopez
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  6. Maria J. Cao
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  7. Maria J. Castro
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Correspondence to Jaime Ruiz-Tovar.

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Informed consent was obtained from all individual participants included in the study.

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All procedures performed in this study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments.

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Marc-Hernández, A., Ruiz-Tovar, J., Jimenez, J.M. et al. Short-Term Changes on Body Composition and Bone Mass After One-Anastomosis Gastric Bypass: a Prospective Observational Study. OBES SURG 30, 3514–3521 (2020). https://doi.org/10.1007/s11695-020-04603-3

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