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Preparation, characterization and antifungal activities of ε-polylysine-decorated nanoliposomes loaded with cinnamaldehyde

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Abstract

Development of materials with green and efficient for restraining the growth of the harmful microorganisms is vital for food safety. Herein, we constructed nanoliposomes with cinnamaldehyde (CIN), an active component of natural cinnamon essential oil, for the long-term inhibition of microbes in food spoilage. In this strategy, cinnamaldehyde nanoliposomes (CIN-NLs) were prepared by the method of thin film dispersion, and then decorated with ε-polylysine (ε-PL) to obtain ε-polylysine/cinnamaldehyde nanoliposomes (ε-PL/CIN-NLs). Results identified that CIN-NLs and ε-PL/CIN-NLs were in spherical and nanoscale, and the nanoliposomes had larger particle size distribution (122.5 ± 3.51–680.4 ± 7.40 nm) and higher encapsulation efficiency (19.4 ± 0.3–30.4 ± 0.2%) after ε-PL (2 mg/mL) decoration. When the CIN concentration was 4 mg/mL, the highest encapsulation efficiency was acquired as 30.4 ± 0.2% by ε-PL/CIN-NLs. CIN-NLs and ε-PL/CIN-NLs showed great activity on inhibiting the growth of Aspergillus flavus and Penicillium citreo-viride, and the inhibition zone diameter of ε-PL/CIN-NLs (26 ± 1.1 mm and 45 ± 1.7 mm, respectively) was significantly larger than that of CIN-NLs (20 ± 1.5 mm and 35 ± 2.1 mm, respectively) in final growth of two fungi. The studies indicated that that ε-PL decoration effectively improved the long-term antifungal activity characteristics of CIN nanoliposomes. Findings from current study can provide a new method to prevent food spoilage and direct future development of green antifungal packing for use in food preservation.

Graphical abstract

The schematic representation of ε-PL/CIN-NLs and the colony growth images of Aspergillus niger and Penicillium citreo-viride.

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References

  1. L. Li, C.J. Zhao, Y.D. Zhang et al., Food Chem. 215, 477–482 (2017)

    Article  CAS  Google Scholar 

  2. M.P. Balaguer, G. Lopez-Carballo, R. Catala, R. Gavara, P. Hernandez-Munoz, Int. J. Food Microbiol. 166(3), 369–377 (2013)

    Article  CAS  Google Scholar 

  3. S. Tiwari, N.K. Dubey, Curr. Opin. Food Sci. 45, 100831 (2022)

    Article  CAS  Google Scholar 

  4. E. Jahdkaran, S.E. Hosseini, A.M. Nafchi, L. Nouri, Food Sci. Nutr. 9(5), 2768–2778 (2021)

    Article  CAS  Google Scholar 

  5. H. Babapour, H. Jalali, A.M. Nafchi, FOOD Sci. Nutr. 9(7), 3893–3905 (2021)

    Article  CAS  Google Scholar 

  6. J. Todd, M. Friedman, J. Patel, D. Jaroni, S. Ravishankar, Int. J. Food Microbiol. 166(1), 193–199 (2013)

    Article  CAS  Google Scholar 

  7. C. Li, W. Chen, S. Siva, H. Cui, L. Lin, Food Packaging and Shelf Life 28, 100647 (2021)

    Article  CAS  Google Scholar 

  8. S.F. Nabavi, A. Di Lorenzo, M. Izadi, E. Sobarzo-Sanchez, M. Daglia, S.M. Nabavi, Nutrients 7(9), 7729–7748 (2015)

    Article  CAS  Google Scholar 

  9. J.L. Wu, H. Liu, S.Y. Ge et al., Food Hydrocoll. 43, 427–435 (2015)

    Article  CAS  Google Scholar 

  10. W.Y. Chen, F.Y. Cheng, C.J. Swing, S.Q. Xia, X.M. Zhang, Chem. Phys. Lipids 223, 104790 (2019)

    Article  CAS  Google Scholar 

  11. I.L. Liakos, C. Menager, N. Guigo et al., ACS Appl. Bio Mater. 2(8), 3484–3497 (2019)

    Article  CAS  Google Scholar 

  12. W. Chen, S. Xia, C. Xiao, Food Biosci. 47, 101686 (2022)

    Article  CAS  Google Scholar 

  13. Y. Gao, Q. Liu, Z.X. Wang et al., J. FOOD Meas. Charact. 15(6), 5326–5336 (2021)

    Article  Google Scholar 

  14. B. Muhoza, B.K. Qi, J.D. Harindintwali, M.Y.F. Koko, S. Zhang, Y. Li, Crit. Rev. Food Sci. Nutr. 1977236 (2021)

  15. B.M. Steiner, D.J. McClements, G. Davidov-Pardo, Trends Food Sci. Technol. 82, 71–81 (2018)

    Article  CAS  Google Scholar 

  16. Y. Wu, K. Wang, Q. Liu et al., Food Chem. 367, 130700 (2022)

    Article  CAS  Google Scholar 

  17. S. Lu, J. Tao, X. Liu, Z. Wen, Food Chem. 371, 131372 (2022)

    Article  CAS  Google Scholar 

  18. C. Tan, B. Feng, X.M. Zhang, W.S. Xia, S.Q. Xia, Food Hydrocoll. 52, 774–784 (2016)

    Article  CAS  Google Scholar 

  19. P. Shao, P. Wang, B. Niu, J. Kang, Int. J. Biol. Macromol. 119, 53–59 (2018)

    Article  CAS  Google Scholar 

  20. N.A. Lopes, C.M.B. Pinilla, A. Brandelli, Food Hydrocoll. 70, 1–7 (2017)

    Article  CAS  Google Scholar 

  21. G.A.T. Kaminski, M.R. Sierakowski, R. Pontarolo, L.A. dos Santos, R.A. de Freitas, Carbohydr. Polym. 140, 129–135 (2016)

  22. X. Wang, F. Cheng, X. Wang, T. Feng, S. Xia, X. Zhang, Int. J. Biol. Macromol. 168, 59–66 (2021)

    Article  CAS  Google Scholar 

  23. A. Catalan-Latorre, M. Ravaghi, M.L. Manca et al., Eur. J. Pharm. Biopharm. 107, 49–55 (2016)

    Article  CAS  Google Scholar 

  24. V. Melis, M.L. Manca, E. Bullita et al., Colloids Surf. B-Biointerfaces 143, 301–308 (2016)

    Article  CAS  Google Scholar 

  25. L. Guo, Y. Li, S. Fang, Y. Pan, J. Chen, Y. Meng, Food Hydrocoll. 130, 107710 (2022)

    Article  CAS  Google Scholar 

  26. L. Ge, Z. Li, M. Han et al., Food Chem. 387, 132885 (2022)

    Article  CAS  Google Scholar 

  27. W. Jiao, X. Liu, Q. Chen et al., Postharvest Biol. Technol. 168, 111270 (2020)

    Article  CAS  Google Scholar 

  28. M.R. Zahi, M.El Hattab, H. Liang, Q. Yuan, Food Chem. 221, 18–23 (2017)

    Article  CAS  Google Scholar 

  29. L. Luppi, T. Babut, E. Petit et al., Polym. Chem. 10(3), 336–344 (2019)

    Article  CAS  Google Scholar 

  30. D. Volodkin, V. Ball, P. Schaaf, J.-C. Voegel, H. Mohwald, Biochim. et Biophys. Acta (BBA) - Biomembr. 1768(2), 280–290 (2007)

    Article  CAS  Google Scholar 

  31. L. Lin, H.Y. Cui, H. Zhou et al., Chem. Commun. 51(13), 2653–2655 (2015)

    Article  CAS  Google Scholar 

  32. L.A. Hergert, G.M. Escandar, Talanta 60(2–3), 235–246 (2003)

    Article  CAS  Google Scholar 

  33. L. Lin, W.Q. Chen, C.Z. Li, H.Y. Cui, Ind. Crops Prod. 140, 111615 (2019)

    Article  CAS  Google Scholar 

  34. M. Khoobchandani, B.K. Ojeswi, N. Ganesh et al., Food Chem. 120(1), 217–224 (2010)

    Article  CAS  Google Scholar 

  35. T. Li, Y. Liu, Q. Qin et al., Food Control 130, 108371 (2021)

    Article  CAS  Google Scholar 

  36. H.Y. Cui, W. Li, L. Lin, J. Food Saf. 37(2), e12302 (2017)

    Article  Google Scholar 

  37. L. Lin, Y.L. Gu, Y.H. Sun, H.Y. Cui, Lwt-Food Sci. Technol. 107, 16–24 (2019)

    Article  CAS  Google Scholar 

  38. F. Hu, X.-F. Tu, K. Thakur et al., Food Chem. Toxicol. 134, 110821 (2019)

    Article  CAS  Google Scholar 

  39. Q. Sun, B. Shang, L. Wang, Z.S. Lu, Y. Liu, Appl. Microbiol. Biotechnol. 100(3), 1355–1364 (2016)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Key Research and Development Program of China (Project No. 2017YFC1600803).

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Authors and Affiliations

  1. State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin, 300457, China

    Tao Wang, Mengnan Wang, Yuan Gao, Xuelian Hu, Haiyang Wang, Guozhen Fang & Shuo Wang

  2. Research Center of Food Science and Human Health, School of Medicine, Nankai University, Tianjin, 300071, China

    Shuo Wang

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  1. Tao Wang
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  2. Mengnan Wang
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  3. Yuan Gao
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  4. Xuelian Hu
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  5. Haiyang Wang
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  6. Guozhen Fang
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  7. Shuo Wang
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Correspondence to Guozhen Fang or Shuo Wang.

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Wang, T., Wang, M., Gao, Y. et al. Preparation, characterization and antifungal activities of ε-polylysine-decorated nanoliposomes loaded with cinnamaldehyde. Food Measure 16, 3712–3721 (2022). https://doi.org/10.1007/s11694-022-01450-x

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  • DOI: https://doi.org/10.1007/s11694-022-01450-x

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