Abstract
Summary
Health status (HS) and influencing factors in HS were evaluated six and 12 months after hip fracture. One-third of the patients did not reach their pre-fracture HS within 1 year. HS before fracture and fall risk could, inter alia, be identified as influencing factors.
Purpose
From a patient’s perspective, regaining pre-fracture health status (HS) is one of the most important factors concerning the outcome after hip fracture. The aim of this study was to evaluate the HS and particularly to identify influencing factors in HS 6 and 12 months after hip fracture.
Methods
A total of 402 patients with hip fractures aged 60 years and older were included. HS was evaluated using the EQ-5D questionnaire pre-fracture and at 6 and 12 months after surgery. Multivariate regression analysis was performed to identify influencing factors in HS at 6 and 12 months. Afterwards, the results in the EQ-5D index were dichotomized into worse and equal/better results than before fracture, and a multivariate logistic regression analysis was performed for the dichotomized variables at 6 and 12 months.
Results
The EQ-5D index decreased from 0.71 before the fracture to 0.60 at 6 months (p < 0.001) and increased slightly to 0.63 at 12 months (p = 0.328). A high pre-fracture EQ-5D index was associated with not reaching the pre-fracture EQ-5D index, and a high Tinetti score at hospital discharge was associated with reaching the pre-fracture EQ-5D index at 6 and 12 months. A high ASA score was an influencing factor behind a lower EQ-5D index than before the fracture at 6 months.
Conclusions
Hip fractures constitute a deep and long-lasting drop in the patients’ HS. Early and intensive physiotherapy and individualized rehabilitation programmes regarding a patient’s living situation before the fracture seem to be essential to improve HS.
Similar content being viewed by others
References
Ström O, Borgström F, Kanis JA, Compston J, Cooper C, McCloskey EV, Jönsson B (2011) Osteoporosis: burden, health care provision and opportunities in the EU: a report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 6:59–155
Kanis JA, Odén A, McCloskey EV, Johansson H, Wahl DA, Cooper C, Life IWGoEaQo (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 23:2239–2256
Cheng SY, Levy AR, Lefaivre KA, Guy P, Kuramoto L, Sobolev B (2011) Geographic trends in incidence of hip fractures: a comprehensive literature review. Osteoporos Int 22:2575–2586
Singer A, Exuzides A, Spangler L, O'Malley C, Colby C, Johnston K, Agodoa I, Baker J, Kagan R (2015) Burden of illness for osteoporotic fractures compared with other serious diseases among postmenopausal women in the United States. Mayo Clin Proc 90:53–62
Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res 22:465–475
Sahota O, Morgan N, Moran CG (2012) The direct cost of acute hip fracture care in care home residents in the UK. Osteoporos Int 23:917–920
Leal J, Gray AM, Prieto-Alhambra D, Arden NK, Cooper C, Javaid MK, Judge A, group Rs (2016) Impact of hip fracture on hospital care costs: a population-based study. Osteoporos Int 27:549–558
Keene GS, Parker MJ, Pryor GA (1993) Mortality and morbidity after hip fractures. BMJ 307:1248–1250
Vaseenon T, Luevitoonvechkij S, Wongtriratanachai P, Rojanasthien S (2010) Long-term mortality after osteoporotic hip fracture in Chiang Mai, Thailand. J Clin Densitom 13:63–67
Bentler SE, Liu L, Obrizan M, Cook EA, Wright KB, Geweke JF, Chrischilles EA, Pavlik CE, Wallace RB, Ohsfeldt RL, Jones MP, Rosenthal GE, Wolinsky FD (2009) The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol 170:1290–1299
da Costa JA, Ribeiro A, Bogas M, Costa L, Varino C, Lucas R, Rodrigues A, Araújo D (2009) Mortality and functional impairment after hip fracture - a prospective study in a Portuguese population. Acta Reumatol Port 34:618–626
Fisher AA, Davis MW, Rubenach SE, Sivakumaran S, Smith PN, Budge MM (2006) Outcomes for older patients with hip fractures: the impact of orthopedic and geriatric medicine cocare. J Orthop Trauma 20:172–178 discussion 179-180
Davidson CW, Merrilees MJ, Wilkinson TJ, McKie JS, Gilchrist NL (2001) Hip fracture mortality and morbidity--can we do better? N Z Med J 114:329–332
Leibson CL, Tosteson AN, Gabriel SE, Ransom JE, Melton LJ (2002) Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study. J Am Geriatr Soc 50:1644–1650
Magaziner J, Simonsick EM, Kashner TM, Hebel JR, Kenzora JE (1990) Predictors of functional recovery one year following hospital discharge for hip fracture: a prospective study. J Gerontol 45:M101–M107
Vergara I, Vrotsou K, Orive M, Gonzalez N, Garcia S, Quintana JM (2014) Factors related to functional prognosis in elderly patients after accidental hip fractures: a prospective cohort study. BMC Geriatr 14:124
Bertram M, Norman R, Kemp L, Vos T (2011) Review of the long-term disability associated with hip fractures. Inj Prev 17:365–370
Ayers DC, Bozic KJ (2013) The importance of outcome measurement in orthopaedics. Clin Orthop Relat Res 471:3409–3411
Peeters CM, Visser E, Van de Ree CL, Gosens T, Den Oudsten BL, De Vries J (2016) Quality of life after hip fracture in the elderly: a systematic literature review. Injury 47:1369–1382
Peterson MG, Allegrante JP, Cornell CN, MacKenzie CR, Robbins L, Horton R, Ganz SB, Augurt A (2002) Measuring recovery after a hip fracture using the SF-36 and Cummings scales. Osteoporos Int 13:296–302
van Balen R, Steyerberg EW, Polder JJ, Ribbers TL, Habbema JD, Cools HJ (2001) Hip fracture in elderly patients: outcomes for function, quality of life, and type of residence. Clin Orthop Relat Res 390:232–243
Hagsten B, Svensson O, Gardulf A (2006) Health-related quality of life and self-reported ability concerning ADL and IADL after hip fracture: a randomized trial. Acta Orthop 77:114–119
Shyu YI, Chen MC, Liang J, Lu JF, Wu CC, Su JY (2004) Changes in quality of life among elderly patients with hip fracture in Taiwan. Osteoporos Int 15:95–102
Randell AG, Nguyen TV, Bhalerao N, Silverman SL, Sambrook PN, Eisman JA (2000) Deterioration in quality of life following hip fracture: a prospective study. Osteoporos Int 11:460–466
Tidermark J, Zethraeus N, Svensson O, Törnkvist H, Ponzer S (2002) Femoral neck fractures in the elderly: functional outcome and quality of life according to EuroQol. Qual Life Res 11:473–481
Beaupre LA, Jones CA, Johnston DW, Wilson DM, Majumdar SR (2012) Recovery of function following a hip fracture in geriatric ambulatory persons living in nursing homes: prospective cohort study. J Am Geriatr Soc 60:1268–1273
Chen LH, Liang J, Chen MC, Wu CC, Cheng HS, Wang HH, Shyu YL (2017) The relationship between preoperative American Society of Anesthesiologists Physical Status Classification scores and functional recovery following hip-fracture surgery. BMC Musculoskelet Disord 18:410
Shyu YI, Chen ML, Chen MC, Wu CC, Su JY (2009) Postoperative pain and its impact on quality of life for hip-fractured older people over 12 months after hospital discharge. J Clin Nurs 18:755–764
Sylliaas H, Thingstad P, Wyller TB, Helbostad J, Sletvold O, Bergland A (2012) Prognostic factors for self-rated function and perceived health in patient living at home three months after a hip fracture. Disabil Rehabil 34:1225–1231
Sanz-Reig J, Lizaur-Utrilla A, Serna-Berna R (2012) Outcomes in nonagenarians after hemiarthroplasty for femoral neck fracture. A prospective matched cohort study. Hip Int 22:113–118
Buecking B, Struewer J, Waldermann A, Horstmann K, Schubert N, Balzer-Geldsetzer M, Dodel R, Bohl K, Ruchholtz S, Bliemel C (2014) What determines health-related quality of life in hip fracture patients at the end of acute care? A prospective observational study. Osteoporos Int 25:475–484
Baker SP, O'Neill B, Haddon W, Long WB (1974) The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14:187–196
EuroQol Group (1990) EuroQol--a new facility for the measurement of health-related quality of life. Health Policy 16:199–208
Gusi N, Olivares PR, Rajendram R (2010) The EQ-5D health-related quality of life questionnaire. In: Preedy VR, Watson RR (eds) Handbook of disease burdens and quality of life measures. Springer, New York, pp 87–99
Van Reenen M, Oppe M (2015) EQ-5D-3L User Guide. https://euroqol.org/wp-content/uploads/2016/09/EQ-5D-3L_UserGuide_2015.pdf. Accessed 31 May 2019
Greiner W, Claes C, Busschbach JJ, von der Schulenburg JM (2005) Validating the EQ-5D with time trade off for the German population. Eur J Health Econ 6:124–130
Saklad M (1941) Grading of patients for surgical procedures. Anesthesiology 2:281–284
Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383
Mahoney FI, Barthel DW (1965) Functional evaluation: the Barthel Index. Md State Med J 14:61–65
Folstein MF, Folstein SE, McHugh PR (1975) “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198
Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1982) Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 17:37–49
Tinetti ME (1986) Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc 34:119–126
Svedbom A, Borgström F, Hernlund E, Ström O, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Uusküla A, Lember M, Kallikorm R, Lesnyak O, McCloskey E, Ershova O, Sanders KM, Silverman S, Tamulaitiene M, Thomas T, Tosteson ANA, Jönsson B, Kanis JA (2018) Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS. Qual Life Res 27:707–716
Peasgood T, Herrmann K, Kanis JA, Brazier JE (2009) An updated systematic review of Health State Utility Values for osteoporosis related conditions. Osteoporos Int 20:853–868
Janssen B, Szende A (2014) Population norms for the EQ-5D. In: Szende A, Janssen B, Cabases J (eds) Self-reported population health: an international perspective based on EQ-5D. Springer, New York, pp 19–30
Borgström F, Lekander I, Ivergård M, Ström O, Svedbom A, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Kallikorm R, Lesnyak O, McCloskey E, Nassonov E, Sanders KM, Silverman S, Tamulaitiene M, Thomas T, Tosteson ANA, Jönsson B, Kanis JA (2013) The International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)--quality of life during the first 4 months after fracture. Osteoporos Int 24:811–823
Zidén L, Frändin K, Kreuter M (2008) Home rehabilitation after hip fracture. A randomized controlled study on balance confidence, physical function and everyday activities. Clin Rehabil 22:1019–1033
Allegrante JP, Peterson MG, Cornell CN et al (2007) Methodological challenges of multiple-component intervention: lessons learned from a randomized controlled trial of functional recovery after hip fracture. HSS J 3:63–70
Kanis JA, Johansson H, Odén A, Harvey NC, Gudnason V, Sanders KM, Sigurdsson G, Siggeirsdottir K, Fitzpatrick LA, Borgström F, McCloskey EV (2018) Characteristics of recurrent fractures. Osteoporos Int 29:1747–1757
Buchholz I, Janssen MF, Kohlmann T, Feng YS (2018) A systematic review of studies comparing the measurement properties of the three-level and five-level versions of the EQ-5D. Pharmacoeconomics 36:645–661
Bharmal M, Thomas J (2006) Comparing the EQ-5D and the SF-6D descriptive systems to assess their ceiling effects in the US general population. Value Health 9:262–271
Janssen MF, Pickard AS, Golicki D, Gudex C, Niewada M, Scalone L, Swinburn P, Busschbach J (2013) Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: a multi-country study. Qual Life Res 22:1717–1727
Lutomski JE, Krabbe PF, Bleijenberg N et al (2017) Measurement properties of the EQ-5D across four major geriatric conditions: findings from TOPICS-MDS. Health Qual Life Outcomes 15:45
Milte R, Crotty M, Miller MD, Whitehead C, Ratcliffe J (2018) Quality of life in older adults following a hip fracture: an empirical comparison of the ICECAP-O and the EQ-5D-3 L instruments. Health Qual Life Outcomes 16:173
Parsons N, Griffin XL, Achten J, Costa ML (2014) Outcome assessment after hip fracture: is EQ-5D the answer? Bone Joint Res 3:69–75
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Institutional review board approval was obtained from the ethics committee (AZ 175/08). All of the patients provided written informed consent for participation in the study.
Conflicts of interest
None.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Hack, J., Buecking, B., Aigner, R. et al. What are the influencing factors in self-rated health status after hip fracture? A prospective study on 402 patients. Arch Osteoporos 14, 92 (2019). https://doi.org/10.1007/s11657-019-0642-x
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s11657-019-0642-x