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In vitro free radical scavenging activity of ethanolic extract of the whole plant of Evolvulus alsinoides (L.) L.

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Abstract

Objective

To identify the free radical scavenging activity of ethanolic extract of Evolvulus alsinoides.

Methods

The free radical scavenging activity was evaluated by in vitro methods like reducing power assay, total antioxidant activity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) reduction, superoxide radical scavenging activity, 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) scavenging activity, hydroxyl radical scavenging assay, and nitric oxide radical scavenging assay, which were studied by using ascorbic acid as standard.

Results

The extract showed significant activities in all antioxidant assays compared with the reference antioxidant ascorbic acid. The total antioxidant activity as well as the reducing power was also found to increase in a dose-dependent manner.

Conclusion

Evolvulus alsinoides may act as a chemopreventive agent, providing antioxidant properties and offering effective protection from free radicals.

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Authors and Affiliations

  1. Department of Biochemistry, Karpagam University, Coimbatore, 641021, India

    Duraisamy Gomathi, Ganesan Ravikumar, Manokaran Kalaiselvi, Balasubramaniam Vidya & Chandrasekar Uma

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  1. Duraisamy Gomathi
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  2. Ganesan Ravikumar
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  3. Manokaran Kalaiselvi
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  4. Balasubramaniam Vidya
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  5. Chandrasekar Uma
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Correspondence to Chandrasekar Uma.

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Gomathi, D., Ravikumar, G., Kalaiselvi, M. et al. In vitro free radical scavenging activity of ethanolic extract of the whole plant of Evolvulus alsinoides (L.) L.. Chin. J. Integr. Med. 21, 453–458 (2015). https://doi.org/10.1007/s11655-014-1763-0

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  • DOI: https://doi.org/10.1007/s11655-014-1763-0

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