ABSTRACT
Background
Multimorbidity presents a significant public health challenge, but regional, rural/urban, and racial/ethnic differences in patterns of multimorbidity in diabetes are poorly understood.
Objective
To describe patterns of multimorbidity in medical and mental health by regional, rural/urban, and racial/ethnic variation in patients with type 2 diabetes mellitus.
Design
Retrospective cohort study from 2002 through 2006
Participants
A national cohort of 892,223 veterans with diabetes
Main Measures
Multimorbidity was the main outcome defined as: the measure of multimorbidity and two categorical outcomes, with pattern of medical and mental health comorbidities combined and separately.
Key Results
Among patients, 52% had 2+ comorbidities, 33% had a single comorbidity, and 14% had no comorbidity; 13.9% had both medical and mental health comorbidities, 70.3% had medical only, and 1.5% had mental health only. The odds of having 3+ comorbidities were nearly fourfold greater in patients 75 years and older relative to patients younger than 50 years (OR=3.95 [95% CI: 3.84, 4.06]). Compared to non-Hispanic whites, the odds of 3+ comorbidities among non-Hispanic blacks were 1.67 times greater (95% CI: 1.63, 1.71). Hispanics were more likely to have a mental health comorbidity alone (OR=1.20 [95% CI: 1.13, 1.28]) than non-Hispanic whites. For patients living in rural areas, the odds were higher of having 3+ comorbidities (OR=1.21 [95% CI: 1.19, 1.23]) and of having both medical and mental health comorbidities (OR=1.15 [95% CI: 1.13, 1.17]) compared to urban dwellers.
Conclusions
Among individuals with diabetes, traditionally disadvantaged groups, including non-Hispanic blacks and rural patients, appear to bear the greatest burden and risk of multimorbidity. Significantly greater odds with increasing number of comorbidities were seen by race/ethnicity, rural residence, and geographic region.
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ACKNOWLEDGMENT
1. This study was supported by grant #IIR-06-219 funded by the VHA Health Services Research and Development (HSR&D) program. The funding agency did not participate in the design or conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript. The manuscript represents the views of the authors and does not reflect those of the VA or HSR&D.
2. Drs. Leonard E Egede and Mulugeta Gebregziabher are the guarantors of this work, and as such, had full access to all data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis.
3. This work has not previously been presented.
Conflict of Interest
The authors each declare that they have no conflict of interest.
Authors’ Contributions
Study concept and design: Egede, Gebregziabher, Axon, Hunt, Lynch
Acquisition of data: Egede
Analysis and interpretation of data: Gebregziabher, Hunt, Payne, Egede
Drafting of the manuscript: Egede, Lynch, Gebregziabher, Axon, Hunt, Payne
Critical revision of the manuscript for important intellectual content: Lynch, Gebregziabher, Axon, Hunt, Payne, Egede
Final approval of manuscript: Lynch, Axon, Gebregziabher, Hunt, Egede, Payne
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Lynch, C.P., Gebregziabher, M., Axon, R.N. et al. Geographic and Racial/Ethnic Variations in Patterns of Multimorbidity Burden in Patients with Type 2 Diabetes. J GEN INTERN MED 30, 25–32 (2015). https://doi.org/10.1007/s11606-014-2990-y
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DOI: https://doi.org/10.1007/s11606-014-2990-y