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Measurement of circumferential tumor extent of colorectal cancer on CT colonography: relation to clinicopathological features and patient prognosis after surgery

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

To examine the relationship between circumferential tumor extent of colorectal cancer (CRC) on CT colonography (CTC) and clinicopathological features including patient prognosis after surgery.

Materials and methods

This retrospective study performed at our institution from January 2013 to December 2019 enrolled 195 consecutive patients (110 men, 85 women; mean age, 64.7 years) with CRC evaluated by contrast-enhanced CTC before surgery. The circumferential tumor extent rate (CER) was measured by CTC in virtual colon dissection (VCD) mode to examine the relation between the CER and clinicopathological features and patient prognosis.

Results

CER had association with tumor invasion depth (T), nodal involvement (N), distant metastasis (M), and stage. The Kruskal–Wallis tests showed significant difference for T, N and the stage (p < 0.0001, p = 0.0021 and p < 0.0001) and Wilcoxon rank sum test showed significant difference for M (p = 0.0015). According to the log-rank test, there were no significant differences in OS or DFS between patients with high and low CER.

Conclusion

Circumferential tumor extent was significantly correlated with TNM categories and stage of CRC, but not with patient prognosis after surgery.

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Authors and Affiliations

  1. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan

    Daisuke Tsurumaru, Noriyuki Takatsu, Satohiro Kai & Kousei Ishigami

  2. Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan

    Eiji Oki

Authors
  1. Daisuke Tsurumaru
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  2. Noriyuki Takatsu
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  3. Satohiro Kai
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  4. Eiji Oki
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  5. Kousei Ishigami
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Corresponding author

Correspondence to Daisuke Tsurumaru.

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The authors declare no conflict of interest associated with this manuscript.

Ethical approval

This study was approved by the institutional review board of our institution.

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Tsurumaru, D., Takatsu, N., Kai, S. et al. Measurement of circumferential tumor extent of colorectal cancer on CT colonography: relation to clinicopathological features and patient prognosis after surgery. Jpn J Radiol 39, 966–972 (2021). https://doi.org/10.1007/s11604-021-01141-5

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  • DOI: https://doi.org/10.1007/s11604-021-01141-5

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