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Perioperative Risk Factors for Post-operative Pneumonia after Type A Acute Aortic Dissection Surgery

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Abstract

Objective

Type A acute aortic dissection (TAAAD) is a dangerous and complicated condition with a high death rate before hospital treatment. Patients who are fortunate to receive prompt surgical treatment still face high in-hospital mortality. A series of post-operative complications further affects the prognosis. Post-operative pneumonia (POP) also leads to great morbidity and mortality. This study aimed to identify the prevalence as well as the risk factors for POP in TAAAD patients and offer references for clinical decisions to further improve the prognosis of patients who survived the surgical procedure.

Methods

The study enrolled 89 TAAAD patients who underwent surgical treatment in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, China from December 2020 to July 2021 and analyzed the perioperative data and outcomes of these patients. Logistic regression analyses were used to identify the risk factors for POP.

Results

In the study, 31.5% of patients developed POP. Patients with POP had higher proportions of severe oxygenation damage, pneumothorax, reintubation, tracheotomy, renal replacement therapy, arrhythmia, gastrointestinal bleeding, and longer duration of mechanical ventilation, fever, ICU stay, and length of stay (all with P<0.05). The in-hospital mortality was 2.3%. Smoking, preoperative white blood cells, and intraoperative transfusion were the independent risk factors for POP in TAAAD.

Conclusion

Patients who underwent TAAAD surgery suffered poorer outcomes when they developed POP. Furthermore, patients with risk factors should be treated with caution.

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Acknowledgements

The authors would like to thank the American Journal Experts for their language polishing.

Author information

Authors and Affiliations

  1. Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Li-juan Hua, Jian-nan Hu, Qian Liu, Chen Bao, Chao Liu, Zi-ling Li & Shu-yun Xu

  2. Department of Respiratory and Critical Care Medicine, Taikang Tongji (Wuhan) Hospital, Wuhan, 430050, China

    Lu-xia Kong

  3. Department of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Jun Chen

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  1. Li-juan Hua
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Correspondence to Shu-yun Xu.

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The authors have no conflicts of interest to declare.

Additional information

This project was supported by the National Natural Science Foundation of China (No. 81370134).

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Hua, Lj., Kong, Lx., Hu, Jn. et al. Perioperative Risk Factors for Post-operative Pneumonia after Type A Acute Aortic Dissection Surgery. CURR MED SCI 43, 69–79 (2023). https://doi.org/10.1007/s11596-022-2659-4

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  • DOI: https://doi.org/10.1007/s11596-022-2659-4

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