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Effect of Acupuncture Cooperated with Low-frequency Repetitive Transcranial Magnetic Stimulation on Chronic Insomnia: A Randomized Clinical Trial

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Summary

The effect of acupuncture cooperated with low-frequency repetitive transcranial magnetic stimulation (rTMS) on chronic insomnia was explored. Seventy-eight patients with chronic insomnia were randomly allocated into two groups: treatment group and control group. In the treatment group, the patients received acupuncture combined with rTMS treatment, and those in the control group were given acupuncture cooperated with sham rTMS treatment, 3 days per week for 4 weeks. Before and after treatment, the primary outcomes including the scores on Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI) and the secondary outcomes including total sleep time (TST), sleep onset latency (SOL), wake after sleep onset (WASO), sleep efficiency (SE%) recorded by sleeping diary and actigraphy were observed in both groups. Seventy-five participants finished the study (38 in treatment group and 37 in control group respectively). After treatment, the scores in the two groups were improved significantly, more significantly in the treatment group than in the control group. It can be inferred that acupuncture cooperated with rTMS can effectively improve sleep quality, enhance the quality of life of patients and has less side effects

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References

  1. Liu L, Liu C, Wang Y, et al. Herbal Medicine for Anxiety, Depression and Insomnia. Curr Neuropharmacol, 2015,13(4):481–493

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Asnis GM, Thomas M, Henderson MA. Pharmacotherapy Treatment Options for Insomnia: A Primer for Clinicians. Int J Mol Sei, 2016,17(1):50

    Article  CAS  Google Scholar 

  3. Trauer JM, Qian MY, Doyle JS, et al. Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis. Ann Intern Med, 2015,163(3):191–204

    Article  PubMed  Google Scholar 

  4. Mao ZJ, Liu CC, Ji SQ, et al. Clinical characteristics of sleep disorders in patients with Parkinson's disease. J Huazhong Univ Sei Technolog Med Sei, 2017,37(1): 100–104

    Article  Google Scholar 

  5. Bhaskar S, Hemavathy D, Prasad S. Prevalence of chronic insomnia in adult patients and its correlation with medical comorbidities. J Family Med Prim Care, 2016,5(4):780–784

    Article  PubMed  PubMed Central  Google Scholar 

  6. Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord, 2011,135(1-3):10–19

    Article  PubMed  Google Scholar 

  7. Staner L. Comorbidity of insomnia and depression. Sleep Med Rev, 2010,14(1):35–46

    Article  PubMed  Google Scholar 

  8. Laugsand LE, Strand LB, Platou C, et al. Insomnia and the risk of incident heart failure: a population study. Eur Heart J, 2014,35(21): 1382–1393

    Article  PubMed  Google Scholar 

  9. Green MJ, Espie CA, Popham F, et al. Insomnia symptoms as a cause of type 2 diabetes Incidence: a 20 year cohort study. BMC Psychiatry, 2017,17(1):94

    Article  PubMed  PubMed Central  Google Scholar 

  10. Cappuccio FP, D'Elia L, Strazzullo P, et al. Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care, 2010,33(2):414–420

    Article  PubMed  Google Scholar 

  11. Almeida CM, Malheiro A. Sleep, immunity and shift workers: A review. Sleep Sei, 2016,9(3): 164–168

    Article  Google Scholar 

  12. Falloon K, Arroll B, Elley CR, et al. The assessment and management of insomnia in primary care. BMJ, 2011,342:d2899

    Article  PubMed  Google Scholar 

  13. Grabowski K, Nowicka-SauerK, Zdrojewski T, etal. Subjective daytime functioning assessment in people with insomnia. Psychiatr Pol, 2017,51(5):833–843

    Article  PubMed  Google Scholar 

  14. National Institutes of Health, Sleep. National Institutes of Health State of the Science Conference statement on Manifestations and Management of Chronic Insomnia in Adults, June 13–15, 2005. Sleep, 2005,28(9):1049-1057

  15. Riemann D, Baglioni C, Bassetti C, et al. European guideline for the diagnosis and treatment of insomnia. J Sleep Res, 2017,26(6):675–700

    Article  PubMed  Google Scholar 

  16. Winkler A, Auer C, Doering BK, et al. Drug treatment of primary insomnia: a meta-analysis of Polysomnographie randomized controlled trials. CNS Drugs, 2014,28(9):799–816

    Article  PubMed  CAS  Google Scholar 

  17. Cheuk DK, Yeung WF, Chung KF, et al. Acupuncture for insomnia. Cochrane Database Syst Rev, 2012(9):CD005472

    Google Scholar 

  18. Guo J, Wang LP, Liu CZ, et al. Efficacy of acupuncture for primary insomnia: a randomized controlled clinical trial. Evid Based Complement Alternat Med, 2013,2013:163850

    PubMed  PubMed Central  Google Scholar 

  19. Park EJ, Lee SJ, Koh DY, et al. Repetitive transcranial magnetic stimulation to treat depression and insomnia with chronic low back pain. Korean J Pain, 2014,27(3):285–289

    Article  PubMed  PubMed Central  Google Scholar 

  20. Lanza G, Cantone M, Lanuzza B, et al. Distinctive patterns of cortical excitability to transcranial magnetic stimulation in obstructive sleep apnea syndrome, restless legs syndrome, insomnia, and sleep deprivation. Sleep Med Rev, 2015,19:39–50

    Article  PubMed  Google Scholar 

  21. Nardone R, Holler Y, Brigo F, et al. Transcranial magnetic stimulation and sleep disorders: pathophysiologic insights. Sleep Med, 2013,14(11): 1047–1058

    Article  PubMed  Google Scholar 

  22. Zheng CS, Liao WJ, Xia WG. Effect of combined low-frequency repetitive transcranial magnetic stimulation and virtual reality training on upper limb function in subacute stroke: a double-blind randomized controlled trail. J Huazhong Univ Sci Technolog Med Sci, 2015,35(2):248–254

    Article  PubMed  Google Scholar 

  23. Winkelman JW. CLINICAL PRACTICE. Insomnia Disorder. N Engl J Med, 2015,373(15):1437–1444

    Article  PubMed  CAS  Google Scholar 

  24. Yeung WF, Chung KF, Leung YK, et al. Traditional needle acupuncture treatment for insomnia: a systematic review of randomized controlled trials. Sleep Med, 2009,10(7):694–704

    Article  PubMed  Google Scholar 

  25. MacPherson H, Altaian DG, Hammerschlag R, et al. Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. J Altern Complement Med, 2010,16(10):ST1–14

    Article  PubMed  Google Scholar 

  26. Blytt KM, Bjorvatn B, Husebo, et al. Clinically significant discrepancies between sleep problems assessed by standard clinical tools and actigraphy. BMC Geriatr, 2017,17(1):253

    Article  PubMed  PubMed Central  Google Scholar 

  27. Wong ML, Lau KNT, Espie CA, et al. Psychometric properties of the Sleep Condition Indicator and Insomnia Severity Index in the evaluation of insomnia disorder. Sleep Med, 2017,33:76–81

    Article  PubMed  Google Scholar 

  28. Mollayeva T, Thurairajah P, Burton K, et al. The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep Med Rev, 2016,25:52–73

    Article  PubMed  Google Scholar 

  29. Spielman AJ, Glovinsky P. The diagnostic interview and differential diagnosis for complaints of insomnia. In: Pressman M, Orr W, eds. Understanding sleep: the evaluation and treatment of sleep disorders. Washington, DC: American Psychological Association Press, 2017:125–160.

    Google Scholar 

  30. Yeung WF, Chung KF, Tso KC, et al. Electroacupuncture for residual insomnia associated with major depressive disorder: a randomized controlled trial. Sleep, 2011,34(6):807–815

    Article  PubMed  PubMed Central  Google Scholar 

  31. Kim SP, Kim JH, Kim BK, et al. Electroacupuncture for insomnia disorder: study protocol for a randomized controlled trial. Trials, 2017,18(1):177

    Article  PubMed  PubMed Central  Google Scholar 

  32. Lyons Z, van der Watt G, Shen Z, et al. Acupuncture and Chinese herbs as treatments for depression: an Australian pilot study. Complement Ther Clin Pract, 2012,18(4):216–220

    Article  PubMed  Google Scholar 

  33. Wang WD, Lu XY, Ng SM, et al. Effects of electroacupuncture on personality traits in depression: a randomized controlled study. Chin J Integr Med, 2013,19(10):777–782

    Article  PubMed  Google Scholar 

  34. Quah-Smith I, Smith C, Crawford JD, et al. Laser acupuncture for depression: a randomised double blind controlled trial using low intensity laser intervention. J Affect Disord, 2013,148(2-3):179–187

    Article  PubMed  Google Scholar 

  35. Yamashita H, Machino A, Shishida K, et al. Complementary and alternative medicine for insomnia. Nihon Rinsho, 2015,73(6):1031–1035

    PubMed  Google Scholar 

  36. Cooper KL, Relton C. Homeopathy for insomnia: a systematic review of research evidence. Sleep Med Rev, 2010,14(5):329–337

    Article  PubMed  Google Scholar 

  37. Riemann D, Baglioni C, Bassetti C, et al. European guideline for the diagnosis and treatment of insomnia. J Sleep Res, 2017,26(6):675–700

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China

    Yang-pu Zhang & Wei-jing Liao

  2. Department of Physical Medicine and Rehabilitation, Hubei Provincial Hospital of Integrated Chinese and Western Medicine, Wuhan, 430015, China

    Yang-pu Zhang & Wen-guang Xia

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  1. Yang-pu Zhang
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  2. Wei-jing Liao
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Correspondence to Wei-jing Liao.

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Zhang, Yp., Liao, Wj. & Xia, Wg. Effect of Acupuncture Cooperated with Low-frequency Repetitive Transcranial Magnetic Stimulation on Chronic Insomnia: A Randomized Clinical Trial. CURR MED SCI 38, 491–498 (2018). https://doi.org/10.1007/s11596-018-1905-2

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  • DOI: https://doi.org/10.1007/s11596-018-1905-2

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