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Microwave synthesis of CdTe/TGA quantum dots and their thermodynamic interaction with bovine serum albumin

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Abstract

The thioglycollic acid (TGA) as a capping agent, CdTe/TGA quantum dots (QDs) with excellent properties were synthesized under microwave irradiation. The TGA/Cd/Te molar ratios, reaction time, temperature and pH are the crucial factors for properties of QDs. The QDs were characterized by UV-vis absorption and fluorescence spectra, transmission electron microscopy and Fourier transform infrared spectroscopy. The experimental results show that when the pH value is 11.5 and molar ratio of TGA:Cd:Te is 1.2:1:0.4 at 100 °C heating for 15 min, the resulted QDs exhibit a high fluorescence quantum yield of 78%. The fluorescence full width at half maximum (FHMW) of QDs is around 23 nm. The products are spherical with average size of 3-5 nm. There is a strong coordination effect between TGA and Cd2+. Moreover, the results of interaction between as-made QDs and bovine serum albumin (BSA) suggest that the QDs-BSA binding reaction is a static quenching. The negative values of free energy (△G<0) suggest that the binding process is spontaneous, △H<0 and △S<0 show that hydrogen bonds and van der Waals interactions play a major role in the binding reaction between QDs and BSA.

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Coal Conversion and New Carbon Materials Hubei Key Laboratory, Wuhan University of Science and Technology, Wuhan, 430081, China

    Ling Ding  (丁玲), Zeze Peng, Tao Liu, Zhengzai Cheng, Mario Gauthier & Feng Liang  (梁峰)

  2. School of Electrical and Eletronic Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China

    Weizhou Shen

  3. Department of Chemistry, University of Waterloo, Ontario, N2L 3G1, Canada

    Mario Gauthier

Authors
  1. Ling Ding  (丁玲)
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  2. Zeze Peng
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  3. Weizhou Shen
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  4. Tao Liu
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  5. Zhengzai Cheng
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  6. Mario Gauthier
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  7. Feng Liang  (梁峰)
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Correspondence to Feng Liang  (梁峰).

Additional information

Funded by the China Scholarship Council and Hubei Provincial Department of Education of China (201308420539), the Science and Technology Research Program of Hubei Provincial Department of Education of China (Q20131105, B2016008), the Coal Conversion and New Carbon Materials Hubei Key Laboratory(Wuhan University of Science and Technology (WKDM201505, WKDM201507) and the Wuhan University of Science and Technology Foundation of China (z00980, 2014XG006)

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Ding, L., Peng, Z., Shen, W. et al. Microwave synthesis of CdTe/TGA quantum dots and their thermodynamic interaction with bovine serum albumin. J. Wuhan Univ. Technol.-Mat. Sci. Edit. 31, 1408–1414 (2016). https://doi.org/10.1007/s11595-016-1546-x

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  • DOI: https://doi.org/10.1007/s11595-016-1546-x

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