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Interventional radiology protocol for treatment of esophagogastric anastomotic leakage

  • CHEST RADIOLOGY
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Abstract

Purpose

We aimed to determine the safety, feasibility and efficacy of interventional radiology method for the management of esophagogastric anastomotic leakage.

Methods

We retrospectively assessed the medical records of 23 consecutive patients with esophagogastric anastomotic leakage treated using intervention protocol. Patients received three-tube method (abscess drainage tube, gastrointestinal decompression tube and jejunal feeding tube) with or without temporary covered esophageal stent placement. Abscess drainage, anti-inflammatory treatment and nutritional support were performed thereafter. The esophageal stents and three tubes were removed after leakage healing.

Results

All patient received three-tube method and eight patients received covered stent placement. All operations were technically successful. After a median of 2.4 months, the stents were successfully removed from five patients. No death, esophageal rupture or massive hemorrhage occurred during procedures. The abscess cavity had markedly decreased in seven patients or disappeared in 16 cases. During follow-up, four patients died of cancer recurrence, one died of heart dysfunction and one died of pulmonary infection. The 1-, 3-, 5-year survival rates were 86.4%, 52.3% and 52.3%, respectively.

Conclusion

Interventional radiology protocol is safe, feasible and efficacious for treatment for esophagogastric anastomotic leakage.

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Funding

This work was supported by National Natural Science Foundation of China (Grant No. 81501569). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.

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Author notes

  1. Yonghua Bi and Xiaoyan Zhu have contributed equally to this work and share co-first authors.

Authors and Affiliations

  1. Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China

    Yonghua Bi, Zepeng Yu, Gang Wu, Xinwei Han & Jianzhuang Ren

  2. Department of Histology and Embryology, College of Basic Medicine, Zhengzhou University, Zhengzhou, China

    Xiaoyan Zhu

Authors
  1. Yonghua Bi
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  2. Xiaoyan Zhu
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  3. Zepeng Yu
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  4. Gang Wu
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  5. Xinwei Han
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  6. Jianzhuang Ren
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Corresponding authors

Correspondence to Xinwei Han or Jianzhuang Ren.

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The authors who have taken part in this study declared that they do not have anything to disclose regarding funding or conflict of interest with respect to this manuscript.

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This study was approved by the institutional review board of Zhengzhou university.

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Bi, Y., Zhu, X., Yu, Z. et al. Interventional radiology protocol for treatment of esophagogastric anastomotic leakage. Radiol med 124, 1253–1261 (2019). https://doi.org/10.1007/s11547-019-01074-0

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  • DOI: https://doi.org/10.1007/s11547-019-01074-0

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