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Evaluating osteoporosis and bone quality in the aging spine: modern considerations for surgical management in the geriatric population

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Abstract

Surgical management paradigms of spinal pathologies in the aging population carry inherent substantial risks, with surgical complications being more prevalent among patients with osteoporosis compared to those with normal bone mineral density. In this narrative review, we aim to highlight important clinical understanding and considerations in perioperative evaluation and management of patients elected to undergo spinal surgery. Osteoporosis is a well-defined risk factor for mechanical complications following spinal surgery, and as such, perioperative optimization of bone health in the setting of surgery for geriatric patients remains a critical research area alongside intraoperative surgical augmentation techniques. Surgical techniques to circumvent challenges with instrumentation of poor bone mineral density have included augmentation of pedicle screw fixation, including segmental bicortical screw fixation techniques, cement augmentation with fenestrated screws, or use of expandable pedicle screws to improve bone-implant interface. Judicious selection of treatment modalities and subsequent perioperative optimization is paramount to minimize surgical complications. Contemporary guidelines and evolving paradigms in perioperative evaluation, optimization, and management of the aging spine include the advent of quantitatively evaluating computed tomography (CT) via assessment of the magnitude of Hounsfield units. Prescribing pharmacotherapeutic agents and monitoring bone health requires a multidisciplinary team approach, including endocrinologists and geriatricians to coordinate high-quality care for advanced-age patients who require surgical management of their spinal disorders.

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Authors and Affiliations

  1. Department of Neurosurgery, Mayo Clinic Arizona, Phoenix, AZ, USA

    Miles Hudson, Jenna Meyer, Chandan Krishna & Joshua Bakhsheshian

  2. Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    Alexander Evans & Zachary A. Smith

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  1. Miles Hudson
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Hudson, M., Meyer, J., Evans, A. et al. Evaluating osteoporosis and bone quality in the aging spine: modern considerations for surgical management in the geriatric population. GeroScience (2024). https://doi.org/10.1007/s11357-024-01171-7

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