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Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts

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Abstract

Natural products may be applied in a wide range of domains, from agriculture to food and pharmaceutical industries. In this study, the antioxidant properties and the capacity to inhibit some enzymatic activities of Euphorbia resinifera and Euphorbia officinarum aqueous extracts and honeys were assessed. The physicochemical characteristics were also evaluated. Higher amounts of iron, copper and aluminium were detected in E. officinarum honey, which may indicate environmental pollution around the beehives or inadequate storage of honey samples. This honey sample showed higher amounts of total phenols and better capacity for scavenging superoxide anion free radicals and DPPH free radicals as compared with E. resinifera honey, but poorer capacity for inhibiting lipoxygenase, acetylcholinesterase, tyrosinase and xanthine oxidase. The ratio plant mass:solvent volume (1:100) and extraction time (1 - 2 h) were associated with higher total phenols and better antioxidant activities and lipoxygenase, acetylcholinesterase and tyrosinase inhibitory activities, regardless of the plant species. The aqueous extracts had systematically higher in vitro activities than the respective honey samples.

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Acknowledgements

The authors acknowledge Manuela David, curator of ALGU Herbarium, in supervising tasks involving the identification, preparation and deposit of the voucher specimens.

Funding

The authors would like to acknowledge the support granted from FCT under the projects UID/MAR/00350/2020; UIDB/05183/2020; UIDB/04326/2020 and UID/AGR/00690/2019

Author information

Authors and Affiliations

  1. Laboratory of Functional Ecology and Environment, Faculty of Science and Technology, University Sidi Mohamed Ben Abdallah, BP 2202, 30 000, Fez, Morocco

    Oumaima Boutoub & Lahsen El Ghadraoui

  2. Mediterranean Institute for Agriculture, Environment and Development, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

    Soukaina El-Guendouz & Maria G. Miguel

  3. CIMO-Centro de Investigação de Montanha, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253, Bragança, Portugal

    Letícia M. Estevinho & Vanessa B. Paula

  4. Laboratory of Phytochemistry, National Agency of Medicinal and Aromatic Plants (ANPMA), BP 159, Principal, 34000, Taounate, Morocco

    Smail Aazza

  5. Centre for Marine and Environmental Research (CIMA), Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

    Brígida Rodrigues

  6. Centre for Marine and Environmental Research (CIMA), Faculdade de Ciências e Tecnologia, Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

    Sara Raposo

  7. Centre of Marine Sciences (CCMAR), University of the Algarve, Gambelas Campus, 8005-139, Faro, Portugal

    Jorge Carlier

  8. Centre of Marine Sciences (CCMAR), Faculdade de Ciências e Tecnologia, University of the Algarve, Gambelas Campus, 8005-139, Faro, Portugal

    Maria C. Costa

Authors
  1. Oumaima Boutoub
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  2. Soukaina El-Guendouz
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  3. Letícia M. Estevinho
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  4. Vanessa B. Paula
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  5. Smail Aazza
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  6. Lahsen El Ghadraoui
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  7. Brígida Rodrigues
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  8. Sara Raposo
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  9. Jorge Carlier
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  10. Maria C. Costa
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  11. Maria G. Miguel
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Correspondence to Maria G. Miguel.

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Responsible Editor: Mohamed M. Abdel-Daim

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Boutoub, O., El-Guendouz, S., Estevinho, L.M. et al. Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts. Environ Sci Pollut Res 28, 503–517 (2021). https://doi.org/10.1007/s11356-020-10489-6

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  • DOI: https://doi.org/10.1007/s11356-020-10489-6

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