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Association between endurance performance, oxidative stress, and antioxidant markers during a running training program in untrained men

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Abstract

Purpose

The aim of this study was to examine the associations between running performance variables, oxidative stress (OS) and antioxidant markers at pre- and post- endurance running training program in untrained men. A second aim was to verify the responses of the performance variables, OS marker malondialdehyde (MDA) and antioxidant markers antioxidant markers catalase (CAT) and superoxide dismutase (SOD), reduced glutathione (GSH) and oxidized (GSSG) after the endurance training program.

Methods

Fifteen untrained men performed 8 weeks of endurance running training. All assessments were performed at pre- and post-endurance training program. The performance variables peak running velocity (Vpeak) and 5-km performance (t5-km), the OS marker MDA and the antioxidant markers CAT, SOD, reduced GSH and oxidized GSSG were analyzed. Absolute and percent changes were calculated (change from pre- to post-training) for each variable. Associations were performed using the Pearson (r) or Spearman (rho) correlation coefficient.

Results

The highest and significant correlations occurred between performance variables and GSSG at post-training (rho = − 0.86 and 0.88, with Vpeak and t5-km, respectively). All other correlations were not significant. Furthermore, 8 weeks of endurance training improved performance and no significant differences were observed in the OS and antioxidant responses between pre- and post-training.

Conclusion

The correlations between running performance variables and OS and antioxidant markers at pre- and post-training in untrained men were not significant and expressive, except for the associations between GSSG and performance variables (Vpeak and t5-km), that were very large. In addition, the endurance training program improved performance and did not significantly change the OS and antioxidant markers in untrained men.

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Acknowledgements

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001.

Funding

Not applicable.

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Authors and Affiliations

  1. Department of Physical Education, State University of Maringá-PR, Av. Colombo, 5790, Maringá, Postal Code: 87020-900, Brazil

    Cecília Segabinazi Peserico & Fabiana Andrade Machado

  2. Associate Post-Graduate Program in Physical Education UEM/UEL, Department of Physical Education, State University of Maringá-PR, Maringá, Brazil

    Fabiana Andrade Machado

  3. Post-Graduate Program of Physiological Sciences, Department of Physiological Sciences, State University of Maringá-PR, Maringá, Brazil

    Fabiana Andrade Machado

Authors
  1. Cecília Segabinazi Peserico
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  2. Fabiana Andrade Machado
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Contributions

All authors contributed to the study conception and design, participated to acquisition of the data, analysis and interpretation of the data and writing the text. All authors have read and approved the final version of the manuscript.

Corresponding author

Correspondence to Cecília Segabinazi Peserico.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Local Human Research Ethics Committee of State University of Maringá (#623.581/2014).

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Informed consent was obtained from all individual participants included in the study.

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Peserico, C.S., Machado, F.A. Association between endurance performance, oxidative stress, and antioxidant markers during a running training program in untrained men. Sport Sci Health 18, 249–256 (2022). https://doi.org/10.1007/s11332-021-00800-4

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  • DOI: https://doi.org/10.1007/s11332-021-00800-4

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