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Expanded home hemodialysis: case reports

  • Nephrology - Original Paper
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Abstract

Among the different hemodialysis (HD) strategies, the short daily hemodialysis performed at home (SDHHD) provides clinical benefits to the patient. Expanded hemodialysis (HDx) employs cutoff medium membranes that exhibit greater clearance capacity of uremic toxins of medium–high molecular weight. This case series study reported the results of seven patients who were transferred to expanded hemodialysis at home (HHDx), from December 2017 to March 2019, over a 12-month follow-up period. The AK-98 monitor and Theranova 400 membrane (Baxter International Inc., Deerfield, IL, USA) were used. The main outcome measures were blood analytical values and drug consumption. The blood levels of β2-microglobulin were significantly reduced (p = 0.0082), while maintaining albumin levels with less use of phosphorus binders. Regarding the safety profile, technique-related adverse events were not reported. According to the results of the current study, HHDx was a safe technique, which additionally had the ability to provide benefits to patients due to its greater purification capacity. Further studies, especially multicenter ones, with a greater number of patients are needed to confirm these results.

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Acknowledgements

Medical writing and editorial assistant services have been provided by Ciencia y Deporte S.L. Support for this assistance was funded by Baxter.

Funding

Medical writing services has been provided by Baxter. Baxter did not participate in either data analysis or redaction of the manuscript.

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Authors and Affiliations

  1. Department of Nephrology, Hospital Universitari General de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain

    Alejandro Pérez-Alba, Javier Reque-Santiváñez, Milagros Vázquez-Gómez & Ramón Pons-Prades

  2. Universidad Politécnica de Madrid, Madrid, Spain

    Alejandro Pérez-Alba

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  1. Alejandro Pérez-Alba
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  2. Javier Reque-Santiváñez
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  3. Milagros Vázquez-Gómez
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  4. Ramón Pons-Prades
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Correspondence to Alejandro Pérez-Alba.

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Dr Alejandro Pérez-Alba has received consulting fees from Baxter during the conduct of the study. The rest of the authors declare that they have no conflict of interest.

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Pérez-Alba, A., Reque-Santiváñez, J., Vázquez-Gómez, M. et al. Expanded home hemodialysis: case reports. Int Urol Nephrol 52, 977–980 (2020). https://doi.org/10.1007/s11255-020-02455-5

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  • DOI: https://doi.org/10.1007/s11255-020-02455-5

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