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Role of dual-source dual-energy computed tomography versus X-ray crystallography in prediction of the stone composition: a retrospective non-randomized pilot study

  • Urology - Original Paper
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Abstract

Purpose

We aimed to evaluate the accuracy of determining stone composition with dual-source (DS) dual-energy (DE) computed tomography (CT).

Methods

A total of 142 patients, diagnosed with urolithiasis and had complete medical records, were included in the study. The number, dimensions, location and CT density of the stones, and dose-length products and effective radiation dose were recorded for every patient. Stone compositions determined with DECT by two radiologists separately were compared with crystallography method.

Results

Among 138 stones with a crystallographic result out of 187 stones evaluated, 58 calcium oxalate, 42 hydroxyapatite, 24 uric acid and 10 cystine stones were detected. DECT showed a sensitivity and negative predictive value of 68.67 and 67.5 % for calcium oxalate. Moreover, DECT was found to be very useful in predicting hydroxyapatite and cystine stones with a 100 % sensitivity and negative predictive value. Cohen kappa correlation test showed a substantial agreement (κ = 0.682) between crystallographic analysis and prediction with DECT-analysis, which was statistically significant (p < 0.001).

Conclusion

In this retrospective study, an unenhanced DECT was found to be accurate for in vivo determination of stone type, and thus it can be used easily without any extra burden to the patient or cost while providing additional information.

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Authors and Affiliations

  1. School of Medicine, Department of Urology, Selcuk University, Konya, Turkey

    Murat Akand, Murat Gul & Ozcan Kilic

  2. School of Medicine, Department of Radiology, Selcuk University, Konya, Turkey

    Mustafa Koplay & Necat Islamoglu

  3. Department of Inspection and Evaluation, Turkish Republic Ministry of Health, General Directorate of Health Services, Ankara, Turkey

    Merter Bora Erdogdu

Authors
  1. Murat Akand
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  2. Mustafa Koplay
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  3. Necat Islamoglu
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  4. Murat Gul
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  5. Ozcan Kilic
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  6. Merter Bora Erdogdu
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Corresponding author

Correspondence to Murat Akand.

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Conflict of interest

All authors declare that they have no conflict of interest.

Funding

This study did not get any form of funding.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study design was approved by the Selcuk University School of Medicine Ethics Committee (Approval Number 2013/265).

Informed consent

Informed consent was not obtained from participants, as this retrospective study was approved by the ethics committee with a waiver of informed consent.

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Akand, M., Koplay, M., Islamoglu, N. et al. Role of dual-source dual-energy computed tomography versus X-ray crystallography in prediction of the stone composition: a retrospective non-randomized pilot study. Int Urol Nephrol 48, 1413–1420 (2016). https://doi.org/10.1007/s11255-016-1320-1

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  • DOI: https://doi.org/10.1007/s11255-016-1320-1

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