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Estrous and ovulatory responses following cervical artificial insemination in Thai-native goats given a new or once-used controlled internal drug release with human chorionic gonadotropin

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Abstract

The study was conducted to compare estrous rate, ovulatory response, plasma progesterone concentrations, and conception rate following cervical artificial insemination in goats given a new or once-used controlled internal drug release (CIDR) device with human chorionic gonadotropin (hCG). Fifty-six Thai-native goats with the average age and body weight of 11 months and 17.3 kg received a 14-day treatment with a new CIDR device (Eazi-BreedTMCIDR®, Pfizer, NY, USA) or a once-used CIDR device. All goats received a 300-IU injection of hCG (Chorulon®, Intervet International B.V., New Zealand) at the day of CIDR removal to induce ovulation. All goats displaying signs of Estrous behavior were artificially inseminated at 12 h after the onset of estrus with frozen semen. No differences in percentage of estrus and ovulation rates were observed; however, goats that received once-used CIDR devices exhibited shorter (P < 0.05) duration of estrus in comparison with new devices (21.4 ± 1.4 h vs. 26.1 ± 1.1 h) and delayed the onset of estrus (47.0 ± 3.6 h vs. 36.5 ± 1.9 h) and the time of ovulation (74.9 ± 3.9 h vs. 64.5 ± 1.3 h), respectively. Progesterone (P4) concentrations were not significantly different (P > 0.05) between treatments during CIDR device insertion and at the time of CIDR removal except on day 4. No significant differences were found in overall conception rates between the treatments. This study indicates that the once-used CIDR device with hCG could be applied to synchronize the estrus and ovulation in small-size Thai-native goats without negative effects on Estrous behavior, ovulatory response, and plasma P4 concentration.

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Acknowledgments

This study was supported by the National Research University (NRU) and Increased Production Efficiency and Meat Quality of Native Beef and Buffalo Research Group, Khon Kaen University, the Thailand Research Fund (TRF), and the National Research Council Thailand (NRCT).

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There is no conflict of interest to declare.

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Authors and Affiliations

  1. Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen, 40002, Thailand

    Chainarong Navanukraw, Vilaivan Khanthusaeng, Aree Kraisoon & Suthipong Uriyapongson

  2. Agricultural Biotechnology Research Center for Sustainable Economy (ABRCSE), Khon Kaen University, Khon Kaen, 40002, Thailand

    Chainarong Navanukraw

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  1. Chainarong Navanukraw
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Correspondence to Chainarong Navanukraw.

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Navanukraw, C., Khanthusaeng, V., Kraisoon, A. et al. Estrous and ovulatory responses following cervical artificial insemination in Thai-native goats given a new or once-used controlled internal drug release with human chorionic gonadotropin. Trop Anim Health Prod 46, 1441–1446 (2014). https://doi.org/10.1007/s11250-014-0662-x

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