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Methods for substitution of the thioxo group with the oxo group in imidazolidine-2-thione derivatives

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Russian Chemical Bulletin Aims and scope

Abstract

The review is focused on the desulfurization of imidazolidine-2-thiones to imidazolidin-2-ones, which are widely applied in the synthesis of natural and synthetic practically useful compounds, primarily biologically active substances. The described methods are systematized in accordance to the key transformations, namely, nucleophilic substitution, oxidation, and more complex cascade reactions.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    A. O. Kuptsova, E. E. Vinogradova, A. N. Kravchenko & G. A. Gazieva

  2. Dmitry Mendeleev University of Chemical Technology of Russia, 9 Miusskaya pl., 125047, Moscow, Russian Federation

    A. O. Kuptsova

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  1. A. O. Kuptsova
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  2. E. E. Vinogradova
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  3. A. N. Kravchenko
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  4. G. A. Gazieva
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Correspondence to G. A. Gazieva.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 885–904, May, 2022.

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

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Kuptsova, A.O., Vinogradova, E.E., Kravchenko, A.N. et al. Methods for substitution of the thioxo group with the oxo group in imidazolidine-2-thione derivatives. Russ Chem Bull 71, 885–904 (2022). https://doi.org/10.1007/s11172-022-3488-0

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