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Arylation of nitromethane with sterically hindered aryl halides

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Abstract

Efficient conditions for Pd-catalyzed cross-coupling of sterically hindered aryl halides with nitromethane were developed to give corresponding aryl nitromethanes. The opportunity to carry out the reaction of polynitromethylation under these conditions was demonstrated, as well as to use the obtained products in the synthesis of bisnitrile oxides.

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Authors and Affiliations

  1. A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 29 Leninsky prosp., 119991, Moscow, Russia

    M. A. Topchiy, A. N. Lysenko, M. A. Rasskazova, A. A. Ageshina, S. A. Rzhevskiy, L. I. Minaeva, M. S. Nechaev & A. F. Asachenko

  2. Department of Chemistry, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskie Gory, 119992, Moscow, Russia

    M. A. Topchiy, S. A. Rzhevskiy, M. S. Nechaev & A. F. Asachenko

Authors
  1. M. A. Topchiy
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  2. A. N. Lysenko
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  3. M. A. Rasskazova
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  4. A. A. Ageshina
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  5. S. A. Rzhevskiy
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  6. L. I. Minaeva
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  7. M. S. Nechaev
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  8. A. F. Asachenko
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Corresponding author

Correspondence to A. F. Asachenko.

Additional information

Dedicated to Academician of the Russian Academy of Sciences O. M. Nefedov on the occasion of his 90th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 59–63, January, 2022.

This work was financially supported by the Russian Science Foundation (Project No. 17-13-01076). The synthesis of nitrile oxides was carried out within the framework of the State Assignment to A. V. Topchiev Institute of Petrochemical Synthesis of the Russian Academy of Sciences.

No human or animal subjects were used in this study.

The authors declare no competing interests.

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Topchiy, M.A., Lysenko, A.N., Rasskazova, M.A. et al. Arylation of nitromethane with sterically hindered aryl halides. Russ Chem Bull 71, 59–63 (2022). https://doi.org/10.1007/s11172-022-3376-7

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