Abstract
A convenient method for the synthesis of high-boiling-point α-(trifluoromethyl)styrenes was proposed. The regioselective synthesis of a series of ethyl 5-aryl-5-(trifluoromethyl)-4,5- dihydroisoxazole-3-carboxylates was conducted by the reaction of ethyl nitroacetate with α-(trifluoromethyl)styrenes in the presence of 1,4-diazabicyclo[2.2.2]octane as a catalyst. The effect of the resulting compounds on seed germination and root formation was studied.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 0099–0103, January, 2019.
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Sigan, A.L., Golubev, A.S., Belyaeva, E.V. et al. Synthesis of ethyl 5-aryl-5-(trifluoromethyl)-4,5-dihydroisoxazole-3-carboxylates, exhibiting plant growth-regulating properties. Russ Chem Bull 68, 99–103 (2019). https://doi.org/10.1007/s11172-019-2422-6
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DOI: https://doi.org/10.1007/s11172-019-2422-6