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Zn salen complex supported on MnCoFe2O4(MCF) magnetic nanoparticles as a catalyst in the synthesis of 3,4-dihydropyrimidin-2 (1H)-ones/thiones (Biginelli-like reaction)

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Abstract

In the present work, a novel Zn salen complex supported on MnCoFe2O4 magnetic nanoparticles, MnCoFe2O4@SiO2-Pr-NH-SA&Zn (MCF@SiO2-Pr-NH-SA&Zn) was easily synthesized by a clean method and fully characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction, Field emission-scanning electron microscopy, Energy dispersive X-ray analyzer, Transmission electron microscopy, Inductively coupled plasma-optical emission spectrometry, Thermogravimetric and Vibrating sample magnetometery analyses. Moreover, the activity of the prepared complex as a heterogeneous catalyst was investigated in Biginelli-like reaction via three component reaction ethyl acetoacetate or dimedone/ or barbituric acid, urea/ or thiourea and different aromatic aldehydes. The structure of new prepared 3,4-dihydropyrimidin-2 (1H)-ones/thions was properly identified by FT-IR, 1H- and 13C-NMR spectroscopy data. Some important advantages of this procedure include easy separation of catalyst by a magnet, short reaction times, excellent yield of products, solvent free, easy work-up and reusability of the catalyst during 6 runs of the used model reaction.

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Acknowledgements

We gratefully acknowledge the financial support of this work by the research council of Arak University.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Arak University, 38156-88138, Arak, Iran

    Najmieh Ahadi, Akbar Mobinikhaledi, Armaghan Fathehesami & Zahra Bagheri

  2. Institute of Nanosciences and Nanotechnology, Arak University, 38156-88138, Arak, Iran

    Najmieh Ahadi & Akbar Mobinikhaledi

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  1. Najmieh Ahadi
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Ahadi, N., Mobinikhaledi, A., Fathehesami, A. et al. Zn salen complex supported on MnCoFe2O4(MCF) magnetic nanoparticles as a catalyst in the synthesis of 3,4-dihydropyrimidin-2 (1H)-ones/thiones (Biginelli-like reaction). Res Chem Intermed 48, 2469–2488 (2022). https://doi.org/10.1007/s11164-022-04709-6

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