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β-Cyclodextrin as an efficient catalyst for the one-pot synthesis of tetrahydrobenzo[b]pyran derivatives in water

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Abstract

Various 4H-benzo[b]pyran derivatives were synthesized via a one-pot three-component condensation of arylaldehyde, malononitrile and dimedone in water using β-cyclodextrin (β-CD) as an efficient catalyst. This method provides several advantages, including mild reaction conditions, operational simplicity, high yields and minimal pollution of the environment.

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Acknowledgments

The work was supported by funds from the National Natural Science Foundation of China: 21442012 and the Chinese Academy of Sciences.

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Authors and Affiliations

  1. Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, People’s Republic of China

    Jun Lu, Xue-wen Fu & Chun Wang

  2. Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, People’s Republic of China

    Jun Lu & Ge Zhang

  3. Institute of Integrated Bioinformedicine and Translational Science, HKBU Shenzhen Research Institute and Continuing Education, Shenzhen, People’s Republic of China

    Jun Lu & Ge Zhang

Authors
  1. Jun Lu
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  2. Xue-wen Fu
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  3. Ge Zhang
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  4. Chun Wang
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Correspondence to Chun Wang.

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Lu, J., Fu, Xw., Zhang, G. et al. β-Cyclodextrin as an efficient catalyst for the one-pot synthesis of tetrahydrobenzo[b]pyran derivatives in water. Res Chem Intermed 42, 417–424 (2016). https://doi.org/10.1007/s11164-015-2027-0

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  • DOI: https://doi.org/10.1007/s11164-015-2027-0

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