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Synthesis and antioxidant activity of bis unsaturated sulfones, bis pyrroles, and bis pyrazoles

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Abstract

The Michael acceptor 1,4-bis-(E)-2-(arylsulfonylvinyl)benzene was exploited to prepare a new series of bis heterocycles-(1,4-phenylene)bis(arylsulfonylpyrrole) and (1,4-phenylene)bis(arylsulfonyl pyrazole). All of the compounds were tested for antioxidant activity. Amongst the tested compounds, 1,4-bis-(E)-2-(arylsulfonylvinyl)benzene (5) was found to be the best potential antioxidant agent.

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Acknowledgments

The authors, G. Lavanya, T. Bhanu Prakash, and G. Sravya are thankful to University Grants Commission (UGC), New Delhi, for the sanction of UGC-BSR fellowship. One of the authors, Dr. A. Padmaja, is grateful to Council of Scientific and Industrial Research (CSIR), New Delhi, for financial assistance under major research project. The authors are also thankful to Prof. C. H. Appa Rao, Department of Bio-Chemistry, S.V. University and Tirupati for providing necessary facilities to carry out the antioxidant activity.

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Authors and Affiliations

  1. Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, Andhra Pradesh, India

    G. Lavanya, T. Bhanu Prakash, G. Sravya, V. Padmavathi & A. Padmaja

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  1. G. Lavanya
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  2. T. Bhanu Prakash
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  3. G. Sravya
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  4. V. Padmavathi
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  5. A. Padmaja
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Correspondence to A. Padmaja.

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Lavanya, G., Prakash, T.B., Sravya, G. et al. Synthesis and antioxidant activity of bis unsaturated sulfones, bis pyrroles, and bis pyrazoles. Res Chem Intermed 41, 8815–8828 (2015). https://doi.org/10.1007/s11164-015-1930-8

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  • DOI: https://doi.org/10.1007/s11164-015-1930-8

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