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Leveraging the Full Continuum of Care to Prevent Opioid Use Disorder

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Abstract

Substance use disorder prevention programs are most effective when matched appropriately to the baseline risk of the population. Individuals who misuse opioids often have unique risk profiles different from those who use other substances such as alcohol or cannabis. However, most substance use prevention programs are geared toward universal audiences, neglecting key inflection points along the continuum of care. The HEAL Prevention Cooperative (HPC) is a unique cohort of research projects that represents a continuum of care, from community-level universal prevention to indicated prevention among older adolescents and young adults who are currently misusing opioids or other substances. This paper describes the theoretical basis for addressing opioid misuse and opioid use disorder across the prevention continuum, using examples from research projects in the HPC.

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Fig. 1

Adapted from Institute of Medicine (1994). Reducing risks for mental disorders: Frontiers for preventive intervention research. The National Academies Press. https://doi.org/10.17226/2139

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Funding

The following grants from the National Institute on Drug Abuse (NIDA) supported the authors in the development of this article: Cance/Adams/Saavedra/Ridenour, U24 DA050182; D’Amico/Palimaru, UG3/UH3 DA050235; Fiellin/Fernandes, UG3/UH3 DA050251; Walton/Bonar, UG3/UH3 DA050173; Komro, UG3/UH3 DA050234; Knight/Knight, UG3/UH3 DA050250; Youn/Rao, UG3/UH3 DA050252. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or its HEAL Initiative.

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This study was conceptualized by representatives of the HEAL Prevention Cooperative (HPC). All authors contributed to drafting the manuscript, provided feedback on the draft, and approved the final manuscript. The views and opinions expressed in this article are those of the authors and should not be construed to represent the views of any of the sponsoring organizations, agencies, or the US government.

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Correspondence to J. D. Cance.

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Conflict of Interest

Dr. Fiellin holds equity with Playbl, Inc., a small commercial venture that focuses on the distribution of evidence-based video games for risk reduction and prevention in youth and young adults. This relationship is extensively managed by Dr. Fiellin and her academic institution.

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Cance, J.D., Adams, E.T., D’Amico, E.J. et al. Leveraging the Full Continuum of Care to Prevent Opioid Use Disorder. Prev Sci 24 (Suppl 1), 30–39 (2023). https://doi.org/10.1007/s11121-023-01545-x

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  • DOI: https://doi.org/10.1007/s11121-023-01545-x

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