Abstract
This mini-review is a compilation of research data on the phytochemistry, pharmacology, and various therapeutic potentials of Argemone mexicana. A. mexicana is a well-known medicinal plant that is used in several ethnomedicinal treatments including for the treatment and management of skin diseases, inflammations, warts, tumors, malaria, jaundice, rheumatism, leprosy, and microbial infections. The plant consists of alkaloids, flavonoids, terpenoids, long-chain aliphatic alcohol, amino acids, carboxylic acid, steroids, carbohydrates, and phenols. The ethnopharmacological relevance of the plant includes the application of the plant extract in Ayurveda and other traditional healthcare as an antioxidant, antimicrobial, anti-inflammatory, anticancer, and larvicidal, as well as for wound healing, hepatoprotection, and sterilizing activities. It can be concluded from this mini-review that A. mexicana has broad applications that are connected to various pharmacological and phytochemical properties of the plant. This work provides some detailed evidence and suggestions for the medicinal application of this plant to improve the condition of mankind.
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Data will be made available upon request.
Abbreviations
- %:
-
Percent or percentage
- A. aegypti :
-
Aedes aegypti
- A. mexicana :
-
Argemone mexicana
- ATPase:
-
Adenosine triphosphatase
- cm:
-
Centimeter
- HeLa:
-
Henrietta Lacks cell line
- HepG2:
-
Human hepatoma cell line
- IC50 :
-
Half-maximal inhibitory concentration
- K+ :
-
Potassium ion
- L. vannamei :
-
Litopenaeus vannamei
- LD50 :
-
Lethal dose50
- m:
-
Meter
- MCF-7:
-
Michigan cancer foundation human breast cancer cell line
- mg/kg:
-
Milligram per kilogram
- MTT:
-
Methylthiazolyldiphenyl-tetrazolium bromide
- NA+ :
-
Sodium ion
- p < 0.05:
-
Probability that the null hypothesis is true
- RdRp:
-
RNA-dependent RNA polymerase
- SARS-CoV-2:
-
Severe acute respiratory syndrome coronavirus 2
- WSSV:
-
White spot syndrome virus
- μg/μl:
-
Microgram per microliter
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JP: formal analysis, investigation, writing–original draft; MO-M: formal analysis, investigation, writing–original draft; ZN: investigation, writing–original draft; PO: investigation, writing–original draft, visualization; MCO: formal analysis, writing–review & editing; EN: investigation, writing–review & editing, visualization; KK: conceptualization, supervision, writing–review & editing, project administration.
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Patocka, J., Ovando-Martinez, M., Navratilova, Z. et al. Argemone mexicana L. (Papaveraceae): chemistry, pharmacology, and toxicology. Phytochem Rev (2024). https://doi.org/10.1007/s11101-024-09918-y
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DOI: https://doi.org/10.1007/s11101-024-09918-y