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The Progress of Poststroke Seizures

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Abstract

A stroke is one of the most common fatal diseases of the nervous system, and the number of strokes per year has increased substantially in recent years. Epilepsy is a poststroke complication that greatly affects the prognosis of patients and reduces their quality of survival. Effective avoidance of causative factors can reduce the risk of a poststroke seizure. However, while many studies have been devoted to elucidating the pathogenesis of poststroke seizures, the literature lacks a comprehensive understanding of the pathogenic mechanism. This article briefly presents the current definition, risk factors, pathogenesis, and prognosis of poststroke seizures based on reported studies and literature reviews, aiming to enrich the available knowledge of this disease.

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Funding

This study was supported by Shandong Provincial Traditional Chinese Medicine Science and Technology Development Plan Project (No. 2019-0369), Incubation Fund of the National Natural Science Foundation of China (No. QYPY2019NSFC0616 and QYPY2021NSFC0618), and Shandong Provincial Medical and Health Science and Technology Development Program (Healthcare Project) (No. 2021BJ000005).

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Authors and Affiliations

  1. Department of Gerontology, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, 16766 Jingshi Road, Jinan, 250014, China

    Cong Xie, Wei Zhao, Xu Zhang & Jinzhi Liu

  2. Laboratory of Microvascular Medicine, Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, 16766 Jingshi Road, Jinan, 250014, China

    Ju Liu

  3. Department of Neurology, Liaocheng People’s Hospital and Liaocheng Clinical School of Shandong First Medical University, 67 Dongchang West Road, Liaocheng, 252000, China

    Jinzhi Liu

  4. Department of Gerontology, Cheeloo College of Medicine, Shandong Provincial Qianfoshan Hospital, Shandong University, 44 Wenhua West Road, Jinan, 250012, China

    Jinzhi Liu

  5. Department of Geriatric Neurology, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, 16766 Jingshi Road, Jinan, 250014, China

    Jinzhi Liu

  6. Department of Neurology, Liaocheng People’s Hospital, Shandong University, No. 27 South Shanda Road, Jinan, Shandong, 250012, PR China

    Zhangyong Xia

  7. Department of Neurology, Liaocheng People’s Hospital and Liaocheng Hospital Affiliated to Shandong First Medical University, 67 Dongchang West Road, Liaocheng, Shandong, 252000, PR China

    Zhangyong Xia

  8. Department of Neurology, the Second People’s Hospital of Liaocheng, No. 306, Health Street, Liaocheng, Shandong, 252000, PR China

    Zhangyong Xia

Authors
  1. Cong Xie
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  2. Wei Zhao
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  3. Xu Zhang
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  4. Ju Liu
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  5. Jinzhi Liu
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Contributions

Cong Xie, Jinzhi Liu, and Zhangyong Xia conceived and designed the study. Cong Xie and Weizhao wrote the draft. Xu Zhang and Ju Liu were responsible for searching the literatures and downloading them. Jinzhi Liu and Zhangyong Xia revised the draft. All authors approved the final version of the manuscript.

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Correspondence to Jinzhi Liu or Zhangyong Xia.

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Cite this article

Xie, C., Zhao, W., Zhang, X. et al. The Progress of Poststroke Seizures. Neurochem Res 49, 887–894 (2024). https://doi.org/10.1007/s11064-023-04079-4

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  • DOI: https://doi.org/10.1007/s11064-023-04079-4

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