Skip to main content
Log in

Non-standard discretization of biological models

  • Published:
Natural Computing Aims and scope Submit manuscript

Abstract

We consider certain types of discretization schemes for differential equations with quadratic nonlinearities, which were introduced by Kahan, and considered in a broader setting by Mickens. These methods have the property that they preserve important structural features of the original systems, such as the behaviour of solutions near to fixed points, and also, where appropriate (e.g. for certain mechanical systems), the property of being volume-preserving, or preserving a symplectic/Poisson structure. Here we focus on the application of Kahan’s method to models of biological systems, in particular to reaction kinetics governed by the Law of Mass Action, and present a general approach to birational discretization, which is applied to population dynamics of Lotka–Volterra type.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  • Al-Kahby H, Dannan Elaydi S (2000) Non-standard discretization methods for some biological models. In: Mickens RE (ed) Applications of nonstandard finite difference schemes. World Scientific, Singapore, pp 155–180

    Chapter  Google Scholar 

  • Celledoni E, McLachlan RI, Owen B, Quispel GRW (2013) Geometric properties of Kahans method. J Phys A 46:025201

    Article  MathSciNet  Google Scholar 

  • Hairer E, Lubich C, Wanner G (2006) Geometric numerical integration: structure-preserving algorithms for ordinary differential equations, 2nd edn. Springer, Berlin

    Google Scholar 

  • Hirota R, Kimura K (2000) Discretization of the Euler top. J Phys Soc Jpn 69:627–630

    Article  MATH  MathSciNet  Google Scholar 

  • Hone ANW, Petrera M (2009) Three-dimensional discrete systems of Hirota–Kimura type and deformed Lie-Poisson algebras. J Geom Mech 1:55–85

    Article  MATH  MathSciNet  Google Scholar 

  • Hone A (2009) On non-standard numerical integration methods for biological oscillators. In: Stepney S, Welch PH, Andrews PS, Timmis J (eds) CoSMoS 2009. Luniver Press, pp 45–65

  • Jang S (2006) Nonstandard finite difference methods and biological models. In: Mickens R (ed) Advances in the applications of nonstandard finite difference schemes. World Scientific, Singapore, pp 423–456

    Google Scholar 

  • Kahan W, Li R-C (1997a) Unconventional schemes for a class of ordinary differential equations—with applications to the Korteweg–de Vries equation. J Comput Phys 134:316–331

    Article  MATH  MathSciNet  Google Scholar 

  • Kahan W, Li R-C (1997b) Composition constants for raising the order of unconventional schemes for ordinary differential equations. Math Comput 88:1089–1099

    Article  MathSciNet  Google Scholar 

  • Mickens RE (1994) Nonstandard finite difference models of differential equations. World Scientific, Singapore

    MATH  Google Scholar 

  • Mickens RE (2003) A nonstandard finite-difference scheme for the Lotka–Volterra system. Appl Numer Math 45:309–314

    Article  MATH  MathSciNet  Google Scholar 

  • Murray JD (2002) Mathematical biology, vol. I, revised 3rd edn. Springer-Verlag, Berlin

  • Patidar KC (2005) On the use of nonstandard finite difference methods. J Differ Equ Appl 11:735–758

    Article  MATH  MathSciNet  Google Scholar 

  • Petrera M, Pfadler A, Suris YuB (2011) On integrability of Hirota–Kimura type discretizations. Regul Chaotic Dyn 16:245–289

    Article  MATH  MathSciNet  Google Scholar 

  • Roeger L-IW (2004) Local stability of Euler’s and Kahan’s methods. J Differ Equ Appl 10:601–614

    Article  MATH  MathSciNet  Google Scholar 

  • Roeger L-IW (2005) A nonstandard discretization method for Lotka–Volterra models that preserves periodic solutions. J Differ Equ Appl 11:721–733

    Article  MATH  MathSciNet  Google Scholar 

  • Roeger L-IW (2006) Nonstandard finite-difference schemes for the Lotka–Volterra systems: generalization of Mickens’s method. J Differ Equ Appl 12:937–948

    Article  MATH  MathSciNet  Google Scholar 

  • Sanz-Serna JM (1994) An unconventional symplectic integrator of W. Kahan. Appl Numer Math 16:245–250

    Article  MATH  MathSciNet  Google Scholar 

Download references

Acknowledgments

KT’s studentship was funded by the EPSRC and the School of Mathematics, Statistics & Actuarial Science, University of Kent. We are grateful to the referees for their comments.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrew Hone.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hone, A., Towler, K. Non-standard discretization of biological models. Nat Comput 14, 39–48 (2015). https://doi.org/10.1007/s11047-014-9463-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11047-014-9463-4

Keywords

Navigation