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Novel sol–gel-derived hardystonite-based biomagnetic nanoparticles for hyperthermia applications

  • Original Paper: Sol-gel and hybrid materials for biological and health (medical) applications
  • Published:
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Abstract

Unique nanosized designed ceramic powders, Fe-doped hardystonite (Fe-HT) with the chemical composition of Ca1.85Fe0.15ZnSi2O7 (0.15Fe-HT) and Ca1.75Fe0.25ZnSi2O7 (0.25Fe-HT), were synthesized by the sol–gel method in order to develop a multifunctional bioactive powder for hyperthermic and tissue engineering applications. Characterization techniques such as X-ray diffraction analysis, transmission electron microscopy, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy were used to investigate the structural characterization of the obtained powders. The results showed that nanocrystalline single-phase Fe-HT powders were successfully synthesized by sol–gel method. The prepared nanopowders had structural properties such as crystallite size (~53 nm), crystallinity degree (~55 %) and lattice strain (~0.355 %) for 0.15Fe-HT and crystallite size (~40 nm), crystallinity degree (~41 %) and lattice strain (~0.401 %) for 0.25Fe-HT. The obtained Fe-HT nanopowders are expected to be a suitable candidate for tissue engineering and also hyperthermia-based cancer therapy.

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Acknowledgments

The authors are grateful for the support to this research by the Isfahan University of Technology.

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Authors and Affiliations

  1. Department of Materials Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran

    Ali Farzin, Rahmatollah Emadi & Mohammadhossein Fathi

  2. Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

    Mohammadhossein Fathi

Authors
  1. Ali Farzin
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  2. Rahmatollah Emadi
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  3. Mohammadhossein Fathi
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Correspondence to Ali Farzin.

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Farzin, A., Emadi, R. & Fathi, M. Novel sol–gel-derived hardystonite-based biomagnetic nanoparticles for hyperthermia applications. J Sol-Gel Sci Technol 80, 402–410 (2016). https://doi.org/10.1007/s10971-016-4100-6

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  • DOI: https://doi.org/10.1007/s10971-016-4100-6

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