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Preparation of radioisotope nanoparticles constructed with Au-ligand framework by self-assembly process for radiotracer

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Abstract

Radioisotope nanoparticles (NPs) constructed with Au-ligand framework were prepared by self-assembly process between radioisotope Au3+ ions and the coordinated ligands in an ethanol/water mixture (1/1, vol %) solution at room temperature for 3 h. The coordinated ligands as bridging organic molecules such as 1,4-bis((1H-imidazol-1-yl)methyl)benzene (BIX), 2,6-bis((1H-imidazol-1-yl)naphthalene (BNX), di(1H-imidazol-1-yl)dimethylsilane (BIS), and 4,4′-bis(pyridin-2-ylmethoxy)biphenyl (BPX) were synthesized by coupling reaction, respectively. The synthesized radioisotope NPs with Au-ligand framework could be used as radiotracers in science, environmental, engineering, and industrial fields.

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Acknowledgments

This work was supported by Radiation Technology R&D program through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning (NRF-2012M2A2A6007040).

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Correspondence to Seong-Ho Choi.

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Oh, MS., Jung, SH. & Choi, SH. Preparation of radioisotope nanoparticles constructed with Au-ligand framework by self-assembly process for radiotracer. J Radioanal Nucl Chem 302, 1151–1158 (2014). https://doi.org/10.1007/s10967-014-3533-z

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  • DOI: https://doi.org/10.1007/s10967-014-3533-z

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