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Using spray-coating method to form PVA coronary artery stents: structure and property evaluations

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Abstract

This study aims to develop coronary artery stents using a spray-coating method. Chitosan is coated onto the polyvinyl alcohol (PVA) fibers in order to form PVA/CS coronary artery stents. The formation of chitosan is evaluated, examining the influences on the PVA/CS stents. The stents are evaluated using surface observation, scanning electron microscope (SEM) observation, thickness measurement, mesh size measurement, braid angle measurement, strut coverage rate measurement, compression strength test, and Fourier transforms infrared spectrometry (FTIR). The test results show that the spray-coating method successfully coats chitosan layer over the PVA/CS stents without sealing the mesh. Moreover, a longer spray coating span improves the compression resistance and maintains the perfect biocompatibility of the PVA/CS stents. This study successfully prepares PVA/CS coronary artery stents that are in a reticular, tubular manner, and coated with a well-formed chitosan layer.

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Acknowledgements

The authors would especially like to thank Ministry of Science and Technology of Taiwan, for financially supporting this research under Contract MOST 105-2221-E-166-006- and MOST 106-2632-E-035-001. Dr. Jia-Horng Lin and Dr. Yueh-Sheng Chen contributed equally to this work.

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Authors and Affiliations

  1. Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung City, 40724, Taiwan

    Mei-Chen Lin, Jan-Yi Lin, Ting An Lin & Shih-Ya Chou

  2. Graduate Institute of Biotechnology and Biomedical Engineering, Central Taiwan University of Science and Technology, Taichung City, 40601, Taiwan

    Ching-Wen Lou

  3. Department of Chemical Engineering and Materials, Ocean College, Minjiang University, Fuzhou, 350108, China

    Ching-Wen Lou & Jia-Horng Lin

  4. Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textiles, Tianjin Polytechnic University, Tianjin, 300387, China

    Ching-Wen Lou & Jia-Horng Lin

  5. College of Textile and Clothing, Qingdao University, Shangdong, 266071, China

    Ching-Wen Lou & Jia-Horng Lin

  6. Department of Cosmeceutic and Graduate Institute of Cosmeceutics, China Medical University, Taichung City, 40402, Taiwan

    Yueh-Sheng Chen

  7. Department of Fiber and Composite Materials, Feng Chia University, Taichung City, 40724, Taiwan

    Jia-Horng Lin

  8. School of Chinese Medicine, China Medical University, Taichung City, 40402, Taiwan

    Jia-Horng Lin

  9. Department of Fashion Design, Asia University, Taichung City, 41354, Taiwan

    Jia-Horng Lin

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  1. Mei-Chen Lin
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  2. Ching-Wen Lou
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  3. Jan-Yi Lin
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  4. Ting An Lin
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  6. Yueh-Sheng Chen
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  7. Jia-Horng Lin
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Correspondence to Jia-Horng Lin.

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Lin, MC., Lou, CW., Lin, JY. et al. Using spray-coating method to form PVA coronary artery stents: structure and property evaluations. J Polym Res 25, 101 (2018). https://doi.org/10.1007/s10965-018-1497-3

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  • DOI: https://doi.org/10.1007/s10965-018-1497-3

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