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Study on preparation and inclusion behavior of inclusion complexes between β-cyclodextrin derivatives with benzophenone

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Journal of Inclusion Phenomena and Macrocyclic Chemistry Aims and scope Submit manuscript

Abstract

In the paper, the two chemically modified β-cyclodextrin derivatives of 4,4´-diaminodiphenyl ether-bridged-bis-β-cyclodextrins (ODA-bis-β-CD) and p-aminobenzenesulfonic acid-β-cyclodextrin (ABS-β-CD) were synthesized, and then these two β-cyclodextrin derivatives were respectively formed into inclusion complexes with benzophenone (BP) by co-precipitation method. The structure of the inclusion complexes were characterized by UV/vis spectroscopy, FT-IR spectroscopy, elemental analysis, 1H NMR spectroscopy and XRD. Spectral titration was performed to study the inclusion behavior of the inclusion complexes. These experiments indicated that two inclusion complexes were formed at a stoichiometric ratio of 1:1 and the inclusion stability constants at different temperatures were calculated using the Benesi–Hildebrand (B–H) equation. The thermodynamic parameters (ΔG°, ΔH°, ΔS°) were obtained. As a result, it was found that the two chemically modified β-cyclodextrins containing BP were exothermic and spontaneous process (ΔG° < 0), and the processes of inclusion complexation were mainly enthalpy driven with negative or minor negative entropic contribution.

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Acknowledgements

This study was supported by National Natural Science Foundation of China (No. 11375084), Nature Science Foundation of Hunan (No. 2017JJ4046), Hunan Provincial Innovation Foundation For Postgraduate (No. CX2017B523).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, University of South China, No. 28, Changsheng Road (West), Zhengxiang District, Hengyang, 421001, Hunan, People’s Republic of China

    Shanxia Deng, Huijun Liu, Caixia Qi, Aohui Yang & Zhendong Li

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  1. Shanxia Deng
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  2. Huijun Liu
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  3. Caixia Qi
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  5. Zhendong Li
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Correspondence to Huijun Liu.

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Deng, S., Liu, H., Qi, C. et al. Study on preparation and inclusion behavior of inclusion complexes between β-cyclodextrin derivatives with benzophenone. J Incl Phenom Macrocycl Chem 90, 321–329 (2018). https://doi.org/10.1007/s10847-018-0787-z

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  • DOI: https://doi.org/10.1007/s10847-018-0787-z

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