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Comparison of a new implantable collamer lens formula to standards formulas using spectral domain optical coherence tomography

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Abstract

Purpose

To use spectral-domain optical coherence tomography (SD-OCT) data to develop a new implantable collamer lens (ICL) sizing formula and compare vault outcomes with the Online Calculation and Ordering System™ (OCOS) and the NK2 formula.

Methods

Consecutive eyes (n = 237) were evaluated that had undergone ICL/toric ICL implantation. Actual ICL vaults were measured, and a what-if analysis was performed to predict vault values with the NK2 formula using SD-OCT data. To develop a new formula (EPB), multiple regression analysis was performed with different parameters than the NK2 formula. Predicted vaults with NK2 and EPB formulas were compared to the actual vaults.

Results

Parameters that were correlated with optimal ICL size were white-to-white, anterior chamber width, lens rise and desired refractive correction. The mean postoperative vault was 489 ± 258 μm. At last visit, 94.5% of eyes were within the manufacturer’s acceptable vault range. Predicted vaults in the acceptable range were 74 and 87% with the NK2 and EPB formulas, respectively. Six percent had a predicted vault less than 100 μm with the EPB formula compared to 1% for actual outcomes. The NK2 formula resulted in a shift toward higher predicted vaults while the EPB formula was similar to the actual postoperative vaults but with slightly more cases with extremely low and high vaults.

Conclusion

SD-OCT data with OCOS result in good postoperative vaults. Further refinement is required to the NK2 for use with SD-OCT data. Although the EPB formula provides acceptable predicted vaults, further refinement with a larger sample size is needed.

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Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

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Authors and Affiliations

Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by AE, and SP. The first draft of the manuscript was written by HB and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Alaa Eldanasoury.

Ethics declarations

Conflict of interest

Authors Pieger and Bains declare they have no financial interests. Author Eldanasoury has received consultant honoraria from Staar Surgical Inc.

Ethics approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Magrabi Eye Hospital.

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Informed consent was obtained from all subjects included in this study.

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Eldanasoury, A., Bains, H. & Pieger, S. Comparison of a new implantable collamer lens formula to standards formulas using spectral domain optical coherence tomography. Int Ophthalmol 43, 4613–4620 (2023). https://doi.org/10.1007/s10792-023-02861-5

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  • DOI: https://doi.org/10.1007/s10792-023-02861-5

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