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Biomaterials Based on Mixtures of Calcium Phosphates and Silicates: Investigation of Possible Production by Precipitation from Water Solutions

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Phase formation processes occurring in the open systems CaX 2M 2HPO4 /M 3PO4–Na2SiO3–H2O are analyzed. It is shown on the basis of the computed values of ΔG of crystallization that it is possible for mixtures of hydroxyapatite and calcium silicate to form in alkaline solutions. It is shown that the precipitation of calcium carbonate is just as likely in ‘wet’ synthesis in air. Ca10(PO4)6(OH)2, CaSiO3, and CaCO3 exhibit bioactivity, which makes it possible to use the system studied for the production of polyphase materials for bone tissue engineering.

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References

  1. S. V. Dorozhkin, “Biphasic, triphasic and multiphasic calcium orthophosphates,” Acta Biomater., 8, 963 – 977 (2012).

    Article  Google Scholar 

  2. O. L. Kubarev, V. S. Komlev, M. Maitts, and S. M. Barinov, “Bioactive composite ceramic in the system hydroxyapatite – tricalcium phosphate,” Dokl. Akad. Nauk, 413(3), 360 – 362 (200).

  3. E. V. Kukueva, V. I. Putlyaev, and T. V. Safronova, “Biphasic resorbable ceramic TCP_PCP obtained from the products of decomposition of octacalcium phosphate,” in: Abstracts of Reports at the Conference on Nanotechnologies in Oncology [in Russian], Moscow (2010), p. 25.

  4. A. P. Solonenko and O. A. Golovanov, “Synthesis and physicochemical study of hydroxyapatite-brushite mixtures,” Zh. Neorg. Khim., 59(1), 12 – 20 (2014).

    Google Scholar 

  5. T. V. Safronova, V. I. Putlyaev, O. A. Avramenko, et al., “Calcium-deficient hydroxyapatite powder for producing tricalcium phosphate based ceramic,” Steklo Keram., No. 1, 27 – 31 (2011); T. V. Safronova, V. I. Putlyaev, O. A. Avramenko, et al., “Calcium-deficient hydroxyapatite powder for producing tricalcium phosphate based ceramic,” Glass Ceram., 68(1 – 2), 28 – 32 (2011).

  6. M. A. Goldberg, V. V. Smirnov, V. M. Ievlev, et al., “Effect of the aging time on the properties of powders in the system hydroxyapatite – calcium carbonate,” Neorg. Mater., 48(2), 225 – 230 (2012).

    Google Scholar 

  7. M. N. Safina, T. V. Safronova, and E. S. Lukin, “Calcium phosphate based ceramic with a resorbable phase and low sintering temperature,” Steklo Keram., No. 7, 19 – 24 (2007); M. N. Safina, T. V. Safronova, and E. S. Lukin, “Calcium phosphate based ceramic with a resorbable phase and low sintering temperature,” Glass Ceram., 64(7 – 8), 238 – 243 (2007).

  8. A. V. Grosser, S. K. Matelo, and T. Kuptsev, “Trace elements and trace elementoses: silicon, fluorine, iodine. Pt. 1,” Profilaktika Segodnya, No. 10, 6 – 14 (2009).

  9. S. Ni and K. Lin, “β-CaSiO3 /β-Ca3(PO4)2 composite materials for hard tissue repair: In vitro studies,” J. Biomed. Mater Res., Part A, 1, 72 – 82 (2008).

  10. L. Radev and V. Hristov, “Sol-gel bioactive glass-ceramics. Part I: Calcium phosphate silicate_wollastonite glass-ceramic,” Cent. Eur. J. Chem., 7, 317 – 321 (2009).

    Google Scholar 

  11. Yu. Yu. Lur’e, Handbook of Analytical Chemistry [in Russian], Khimiya, Moscow (1989).

    Google Scholar 

  12. S. Koutsopoulos and E. Dalas, “Hydroxyapatite crystallization in the presence of serine, tyrosine and hydroxyproline amino acids with polar side groups,” J. Cryst. Growth, 216, 443 – 449 (2000).

    Article  Google Scholar 

  13. J. J. Chen, J. J. Thomas, H. F. W. Taylor, and H. M. Jennings, “Solubility and structure of calcium silicate hydrate,” Cement Concrete Res., 34, 1499 – 1519 (2004).

    Article  Google Scholar 

  14. S. M. Barinov and V. S. Komlev, Bioceramics Based on Calcium Phosphates [in Russian], Nauka, Moscow (2005).

    Google Scholar 

  15. V. I. Putlyaev and T. V. Safronova, “A new generation of calcium phosphate biomaterials: The role of phase and chemical compositions,” Steklo Keram., No. 3, 30 – 33 (2006); V. I. Putlyaev and T. V. Safronova, “A new generation of calcium phosphate biomaterials: The role of phase and chemical compositions,” Glass Ceram., 63(3 – 4), 99 – 102 (2006).

  16. S. P. Thompson, S. J. Day, J. E. Parker, et al., “Fine-grained amorphous calcium silicate CaSiO3 from vacuum dried sol–gel: Production, characterisation and thermal behaviour,” J. Non-Cryst. Solids, 358, 885 – 892 (2012).

    Article  Google Scholar 

  17. P. S. Gordienko, S. B. Yarusova, A. P. Suponina, et al., “Effect of hydration and atmospheric air on the sorption properties and phase composition of calcium hydrosilicate,” Ekolog. Khim., 23(2), 102 – 109 (2014).

    Google Scholar 

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Correspondence to A. P. Solonenko.

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Translated from Steklo i Keramika, No. 10, pp. 37 – 40, October, 2016.

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Solonenko, A.P. Biomaterials Based on Mixtures of Calcium Phosphates and Silicates: Investigation of Possible Production by Precipitation from Water Solutions. Glass Ceram 73, 386–389 (2017). https://doi.org/10.1007/s10717-017-9895-2

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