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α-Transducin and α-gustducin immunoreactive cells in the stomach of common sole (Solea solea) fed with mussel meal

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Abstract

Vertebrates perceive a variety of exogenous substances using two main chemosensory systems, taste and olfaction. The taste perception occurs through the interaction of taste receptors associated with specific G protein subunits such as α-transducin (Gαtran) and α-gustducin (Gαgust). Aquatic vertebrates are also provided with a chemosensory system consisting of solitary chemosensory cells distributed to the oropharynx and skin. In this study, we identified Gαtran and Gαgust-immunoreactive cells intermingled with non-labeled epithelial cells in the gastric mucosa of the common sole. A long-term diet with increasing concentrations of mussel meal in the protein component of a conventional fish meal-based diet induced a dose-dependent increase in the gastric epithelial area and density of Gαtran and Gαgust immunoreactive cells. These findings suggest that taste-related molecules are regulated by changes in diet formulation in common sole aquaculture.

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Acknowledgments

This study was financed by the Department of Veterinary Medical Science, University of Bologna. The authors thank Drs. Roberto De Giorgio (University of Bologna, Italy) and Catia Sternini (University of California at Los Angeles) for their comments on the manuscript.

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Authors and Affiliations

  1. Department of Veterinary Medical Science, University of Bologna, Via Tolara di Sopra, 50, 40064, Ozzano dell’emilia, Bologna, Italy

    Maurizio Mazzoni, Alessio Bonaldo, Pier Paolo Gatta, Claudia Vallorani, Marco Canova & Paolo Clavenzani

  2. Department of Medical and Surgical Sciences, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

    Rocco Latorre

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  1. Maurizio Mazzoni
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  2. Alessio Bonaldo
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  3. Pier Paolo Gatta
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  4. Claudia Vallorani
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  6. Marco Canova
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  7. Paolo Clavenzani
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Correspondence to Maurizio Mazzoni.

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Mazzoni, M., Bonaldo, A., Gatta, P.P. et al. α-Transducin and α-gustducin immunoreactive cells in the stomach of common sole (Solea solea) fed with mussel meal. Fish Physiol Biochem 41, 603–612 (2015). https://doi.org/10.1007/s10695-015-0031-3

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