Abstract
A new triterpene ester (1) together with eight known compounds (2–9) were isolated from the leaves of Cadaba farinosa Forssk. Their chemical structures were established on the basis of physical, chemical, and spectroscopic methods (IR, 1D and 2D NMR, and mass spectral analyses) to be: lupeol-3-O-decanoate (1), lupeol (2), β-sitosterol (3), ursolic acid (4), 12-aminododecanoic (5), dillenetin-3-O-β-d-glucopyranoside (6), stachydrine (7), 3-hydroxy-stachydrine (8), and quercetin-3-O-β-d-glucopyranoside (9). That is the first report for the isolation of compound 5 from a plant source. Compounds 5, 6, and 9 were evaluated for their antioxidant activity.
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Acknowledgments
The authors are grateful to Dr. Volker Brecht (nuclear magnetics resonance, institute fuer pharmazeutische wissenschaften, Albert-Ludwigs-Universität, Freiburg, Germany) for MS spectral measurements.
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Al-Musayeib, N.M., Mohamed, G.A., Ibrahim, S.R.M. et al. Lupeol-3-O-decanoate, a new triterpene ester from Cadaba farinosa Forssk. growing in Saudi Arabia. Med Chem Res 22, 5297–5302 (2013). https://doi.org/10.1007/s00044-013-0536-1
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DOI: https://doi.org/10.1007/s00044-013-0536-1