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A New Diarylheptanoid Bearing the Flavonol Moiety from Alpinia officinarum and its Xanthine Oxidase Inhibitory Activity

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Chemistry of Natural Compounds Aims and scope

A novel diarylheptanoid-flavonol dimer (1), named officinin C, was isolated from the rhizomes of Alpinia officinarum Hance. The structure elucidation was accomplished by HR-ESI-MS and 1D and 2D NMR methods. Its xanthine oxidase inhibitory activity was tested along with officinin A (2). At the concentration of 25 μM, compounds 1 and 2 can reach 57 and 52% inhibition rates against xanthine oxidase.

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Acknowledgment

The authors gratefully acknowledge the financial support of this study by the Scientific Research Program Funding Projects of Hubei Provincal Department of Education (No. D20201606) and the Hubei Province Key Laboratory of Conservation Biology for Shennongjia Golden Monkey Foundation (No. SNJKL2017003).

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Authors and Affiliations

  1. School of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, 430023, Wuhan, P. R. China

    Shu Hui Wu, Yao Xin Zhao & Ling Zhao

  2. Hubei Province Key Laboratory of Conservation Biology for Shennongjia Golden Monkey, Shennongjia National Park, Muyu County, Shennongjia Forestry Region, 442411, Hubei, P. R. China

    Jie Zhou & Guo Fei Ma

Authors
  1. Shu Hui Wu
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  2. Yao Xin Zhao
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  3. Jie Zhou
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  4. Guo Fei Ma
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  5. Ling Zhao
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Corresponding author

Correspondence to Ling Zhao.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2021, pp. 25–27.

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Wu, S.H., Zhao, Y.X., Zhou, J. et al. A New Diarylheptanoid Bearing the Flavonol Moiety from Alpinia officinarum and its Xanthine Oxidase Inhibitory Activity. Chem Nat Compd 57, 26–29 (2021). https://doi.org/10.1007/s10600-021-03273-6

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  • DOI: https://doi.org/10.1007/s10600-021-03273-6

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