Two new isoquinoline alkaloids, fuscatine A (1) and fuscatine B (2), along with 21 compounds including eight isoquinoline alkaloids, northalifoline (3), thalifoline (4), corydaldine (5), N-methylcorydaldine (6), (6,7-dimethoxyisoquinolinyl)-(4′-methoxyphenyl)-methanone (7),(6,7-dimethoxyisoquinolinyl)-(4′-hydroxyphenyl)-methanone (8), liriodenine (9), and corydine (10); two steroids, β-sitosterone and stigmasterone; six benzenoids, p-hydroxybenzaldehyde, p-hydroxybenzoic acid, 3,4-dimethoxybenzoic acid, methylparaben, syringic acid, and coniferyl aldehyde; one quinone 2,6-dimethoxy-p-benzoquinone, and one sesquiterpene, caryophyllene oxide, are isolated from the stems of Michelia fuscata (Magnoliaceae). These compounds were characterized and identified by physical and spectral analysis.
Similar content being viewed by others
References
C. T. Huang, S. J. Chen, H. M. Wu, Y. F. Kang, H. L. Chen, W. J. Li, H. T. Li, and C. Y. Chen, Chem. Nat. Compd., 50, 1047 (2014).
S. Chericoni, L. Testai, E. Campeol, V. Calderone, I. Morelli, and E. Martinotti, J. Ethnopharmacol., 91, 263 (2004).
W. L. Lo, L. Y. Huang, H. M. Wang, and C. Y. Chen, Chem. Nat. Compd., 46, 664 (2010).
H. M. Wang, W. L. Yang, S. C. Yang, and C. Y. Chen, Chem. Nat. Compd., 46, 327 (2010).
M. J. Cheng, W. L. Lo, J. C. Huang, Y. T. Yeh, Z. L. Hong, Y. C. Lu, M. S. Chang, and C. Y. Chen, Nat. Prod. Res., 24, 682 (2010).
H. M. Wang, W. L. Lo, L. Y. Huang, Y. D. Wang, and C. Y. Chen, Nat. Prod. Res., 24, 398 (2010).
C. Y. Chen, L. Y. Huang, L. J. Chen, W. L. Lo, S. Y. Kuo, Y. D. Wang, S. H. Kuo, and T. J. Hsieh, Chem. Nat. Compd., 44, 137 (2008).
C. Y. Chen, T. Z. Liu, W. C. Tseng, F. J. Lu, R. P. Hung, C. H. Chen, and C. H. Chen, Food Chem. Toxicol., 46, 2694 (2008).
C. Y. Chen, F. R. Chang, C. M. Teng, and Y. C. Wu, J. Chin. Chem. Soc., 46, 77 (1999).
N. Kucukboyaci, F. Bingol, B. Sener, J. P. Kutney, and N. Stoynov, Nat. Prod. Sci., 4, 257 (1998).
Y. Su, S. Li, N. Li, L. Chen, J. Zhang, and J. Wang, J. Med. Plants Res., 5, 5428 (2011).
P. Pudjiastuti, M. R. Mukhtar, A. H. A. Hadi, N. Saidi, H. Morita, M. Litaudon, and K. Awang, Molecules, 15, 2339 (2010).
H. W. Gibson, F. D. Popp, and A. C. Noble, J. Heterocycl. Chem., 3, 99 (1966).
C. Y. Chen, F. R. Chang, and Y. C. Wu, J. Chin. Chem. Soc., 44, 313 (1997).
C. Thebtaranonth, Y. Thebtaranonth, S. Wanauppathamkul, and Y. Yuthavong, Phytochemistry, 31, 2645 (1999).
W. Werner and S. Dieter, Tetrahedron Lett., 21, 1927 (1980).
C. Weimar, S. Angerer, and W. Wiegrebe, Arch. Pharm., 324, 509 (1991).
Acknowledgment
This work was financially supported by the Ministry of Science and Technology of the Republic of China under Grant No. MOST 104-2320-B-242-001-MY3 (C. Y. Chen).
Author information
Authors and Affiliations
Corresponding authors
Additional information
Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2017, pp. 428–430.
Rights and permissions
About this article
Cite this article
Li, H.T., Kao, C.L., Tsai, C.R. et al. Isoquinoline Alkaloids from Michelia fuscata . Chem Nat Compd 53, 504–507 (2017). https://doi.org/10.1007/s10600-017-2032-1
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-017-2032-1