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New Flavones from Garcinia bracteata and Their Biological Activities

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Chemistry of Natural Compounds Aims and scope

Investigation of an organic extract of the stems of Garcinia bracteata led to the isolation of two new flavones, named bracflavones A (1) and B (2). Their structures were elucidated by spectroscopic evidence. The compounds feature an isopropoxy group at C-3 compared with related known flavonoids isolated from the genus Garcinia. Compounds 1 and 2 were tested for their cytotoxicity. The results revealed that compound 1 showed high cytotoxicity against A549 and PC3 cell lines, and compound 2 showed high cytotoxicity against NB4, A549, SH-SY5Y, PC3, and MCF7 cell lines.

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References

  1. X. W. Li, J. Li, and P. F. Stevens, Flora of China, Vol. 13, Science Press, Beijing, 2007, p. 43.

  2. Z. Na, H. B. Hu, and Q. F. Fan, Chin. Chem. Lett., 21, 443 (2010).

    Article  CAS  Google Scholar 

  3. Z. Na, H. B. Hu, and Q. F. Fan, Helv. Chim. Acta, 5, 958 (2010).

    Article  Google Scholar 

  4. O. Thoison, J. Fahy, V. Dumontet, A. Chiaroni, C. Riche, M. V. Tri, and T. J. Seveneta, J. Nat. Prod., 63, 441 (2000).

    Article  CAS  PubMed  Google Scholar 

  5. O. Thoison, D. D. Cuong, A. Gramain, A. Chiaroni, N. V. Hung, and T. Seveneta, Tetrahedron, 61, 8529 (2005).

    Article  CAS  Google Scholar 

  6. J. Shen, Z. Tian, and J. S. Yang, Pharmazie, 62, 549 (2007).

    CAS  PubMed  Google Scholar 

  7. J. H. Wu, Y. T. Tung, C. F. Chyu, S. C. Chien, S. Y. Wang, S. T. Chang, and Y. H. Kuo, J. Wood Sci., 54, 383 (2008).

    Article  Google Scholar 

  8. S. Deachathai, W. Mahabusarakam, S. Phongpaichit, and W. C. Taylor, Phytochemistry, 66, 2368 (2005).

    Article  CAS  PubMed  Google Scholar 

  9. S. Deachathai, W. Mahabusarakam, S. Phongpaichit, W. C. Taylor, Y. J. Zhang, and C. R. Yang, Phytochemistry, 67, 464 (2006).

    Article  CAS  PubMed  Google Scholar 

  10. J. Ngoupayo, D. T. Noungoue, B. N. Lenta, T. K. Tabopda, S. N. Khan, S. Ngouela, M. A. Shaiq, and E. Tsamo, Nat. Prod. Commun., 2, 1141 (2007).

    CAS  Google Scholar 

  11. T. Mosmann, J. Immunol. Methods, 65, 55 (1983).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgment

This research was supported by the National Natural Science Foundation of China (No. 21002085), the Excellent Scientific and Technological Team of Yunnan High School (2010CI08), the Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team (2011HC008), and start-up funds of Yunnan University of Nationalities.

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Authors and Affiliations

  1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, 650031, Kunming, P. R. China

    Qiufen Hu, Deyun Niu, Zongyan Yang, Guoli Zhao, Zhongxiu Yang & Xuemei Gao

  2. Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, 650106, Kunming, P. R China

    Deyun Niu, Sujuan Wang, Yunhua Qin & Zhangyu Chen

  3. China Tobacco Yunnan Industry Company (Ltd.), 650000, Kunming, P. R. China

    Zhangyu Chen

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  1. Qiufen Hu
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  2. Deyun Niu
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  3. Sujuan Wang
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  4. Yunhua Qin
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  5. Zongyan Yang
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  6. Guoli Zhao
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  7. Zhongxiu Yang
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  8. Xuemei Gao
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  9. Zhangyu Chen
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Corresponding author

Correspondence to Xuemei Gao.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2014, pp. 856–858.

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Hu, Q., Niu, D., Wang, S. et al. New Flavones from Garcinia bracteata and Their Biological Activities. Chem Nat Compd 50, 985–988 (2014). https://doi.org/10.1007/s10600-014-1142-2

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  • DOI: https://doi.org/10.1007/s10600-014-1142-2

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