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A New Furanocoumarin from the Roots of Angelica oncosepala

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Chemistry of Natural Compounds Aims and scope

A new furanocoumarin, 5-(2″,3″-dihydroxy-3″-methylbutyloxy)-8-(2″′-hydroxy-3″′-methyl-3″′-butylenoxy)-psoralen, named oncosepalin B (1), was isolated from the roots of Angelica oncosepala. The structure of the new compound was identified on the basis of spectroscopic methods, especially extensive 1D and 2D NMR spectra analysis. Compound 1 showed weak inhibition of HL-60 human tumor cell line with an IC50 value of 17.05 μM.

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Acknowledgment

This work was financially supported by the Natural Science Foundation of Yunnan Province (No. 2011FB058) and the National Natural Science Foundation of China (No. 21102060).

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Authors and Affiliations

  1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, 650500, Kunming, Yunnan, P. R. China

    Chen Qing, Yi-Ping Zhou, Bin Zheng, Ming Luo & Xian Li

  2. The Gynaecology Department of the First People’s Hospital of Yunnan Province, 650032, Kunming, Yunnan, P. R. China

    Rong Zi

Authors
  1. Chen Qing
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  2. Yi-Ping Zhou
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  3. Rong Zi
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  4. Bin Zheng
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  5. Ming Luo
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  6. Xian Li
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Corresponding author

Correspondence to Xian Li.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2014, pp. 223–224.

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Qing, C., Zhou, YP., Zi, R. et al. A New Furanocoumarin from the Roots of Angelica oncosepala . Chem Nat Compd 50, 251–253 (2014). https://doi.org/10.1007/s10600-014-0924-x

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  • DOI: https://doi.org/10.1007/s10600-014-0924-x

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