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4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

Different [3,4]-fused polycyclic 2H-chromen-2-ones can be prepared in a stereoselective fashion starting from 4-hydroxycoumarins as nucleophilic synthones. Herein we report a brief overview of the most recent methods including Pd-catalyzed [3+3] annulation processes, organocatalytic one-pot and domino Michael addition/cyclization, tandem conjugate addition/hydroxyalkylation, and organocascade catalytic reaction.

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Authors and Affiliations

  1. Department of Pharmacy – Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, Bari, 70125, Italy

    Mariagrazia Rullo & Leonardo Pisani

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  1. Mariagrazia Rullo
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  2. Leonardo Pisani
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Correspondence to Leonardo Pisani.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(4), 394–396

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Rullo, M., Pisani, L. 4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview). Chem Heterocycl Comp 54, 394–396 (2018). https://doi.org/10.1007/s10593-018-2281-3

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  • DOI: https://doi.org/10.1007/s10593-018-2281-3

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