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Global prevalence of depression among breast cancer patients: a systematic review and meta-analysis

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Abstract

Purpose

Depression in patients with breast cancer imposes huge costs to patients, families, and healthcare systems. The present study aimed at evaluating the global prevalence depression among patients with breast cancer.

Methods

In this meta-analysis, three electronic databases (PubMed, Web of Science, and Scopus) were searched from 1 January, 2000 until 30 March, 2019. The Hoy tool was used to evaluate the quality of the articles included in the meta-analysis. The search, screening, quality evaluation, and data extraction were carried out by two of the researchers.

Results

Of 47,424 studies, 72 studies performed in 30 countries entered the final stage of analysis. The global prevalence of depression was 32.2%. Specifically, the prevalence of depression was highest in the Eastern Mediterranean region and twice as high in middle-income countries as compared to developed countries.

Conclusions

Regarding the high prevalence of depression in patients with breast cancer, it is vital to carry out screening within standard time periods and offer the necessary emotional support.

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Authors and Affiliations

  1. Department of Nursing Education, Nursing and Midwifery School, Jiroft University of Medical Sciences, Jiroft, Iran

    Motahare Pilevarzadeh

  2. Midwifery Department, Zabol University of Medical Sciences, Zabol, Iran

    Mehrbanoo Amirshahi

  3. Department of Cardiology, Shohada Hospital, Urmia University of Medical Science, Urmia, Iran

    Roghaiyeh Afsargharehbagh

  4. Student Research Committee, Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Hosein Rafiemanesh

  5. Clinical Immunology Research Center, Department of Internal Medicine, Hematology and Medical Oncology Ward, Ali-Ebne-Abitalelb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran

    Seyed-Mehdi Hashemi

  6. Student Research Committee, Nursing and Midwifery School, Iran University of Medical Sciences, Tehran, Iran

    Abbas Balouchi

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  1. Motahare Pilevarzadeh
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  3. Roghaiyeh Afsargharehbagh
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  4. Hosein Rafiemanesh
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  5. Seyed-Mehdi Hashemi
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  6. Abbas Balouchi
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Correspondence to Seyed-Mehdi Hashemi.

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Pilevarzadeh, M., Amirshahi, M., Afsargharehbagh, R. et al. Global prevalence of depression among breast cancer patients: a systematic review and meta-analysis. Breast Cancer Res Treat 176, 519–533 (2019). https://doi.org/10.1007/s10549-019-05271-3

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