Skip to main content
SpringerLink
Log in

A Portable Device for Rapid Assessment of the Functional State of the Hemostasis System

  • Published:
Biomedical Engineering Aims and scope

We present here the results obtained during the development of a portable device for rapid assessment of the functional state of the homeostasis system based on analysis of capillary blood. Vascular-thrombocytic hemostasis was assessed in volunteers in real time using the device. The results of piezocoagulography conducted using the portable device were compared to the results obtained by low-frequency piezothromboelastography (Mednord ARP-01M). These data showed a strong correlation, evidencing the potential of the method and device developed here for studies of the functional state of the hemostasis system at the patient’s bedside or outside hospital.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Galstyan, G. M. and Sukhanova, G. A., “Introduction to hemostasis and current blood products and their effects on coagulation,” Med. Sovet., No. 5–6, 11–16 (2013).

  2. Zabolotskikh, I. B., Sin’kov, S. V., and Shaposhnikov, S. A., Diagnosis and Correction of Disorders of the Hemostasis System [in Russian], Prakticheskaya Meditsina, Moscow (2008).

    Google Scholar 

  3. Tyutrin, I. I., Zhukov, E. L., and Slizevich, D. S., A Device and Method for Rapid Assessment of the Functional State of the Hemostasis System, RF Patent No. 269393 (2018).

  4. Udut, V. V., Tyutrin, I. I., Kotlovskaya, L. Yu., Solov’ev, M. A., and Zhukov E. L., “Technology for low-frequency piezothromboelastography for assessment of hemostatic potential,” Vestn. Nov. Med. Tekhnol., No. 4, 104–113 (2016).

    Google Scholar 

  5. Vavilova, T. V., “How to devise an investigation program for patients with blood clotting disorders,” Aterotromboz., No. 2, 95–108 (2017).

  6. Magnette, A., Chatelain, M., Chatelain, B., ten Cate, H., and Mullier, F., “Pre-analytical issues in the haemostasis laboratory: Guidance for the clinical laboratories,” Thromb. J., 14, 49 (2016).

    Article  CAS  Google Scholar 

  7. Tyutrin, I. I., Ovsyannikov, Yu. A., Sorokozherdiev, V. O., Shpisman, M. N., Shipakov, V. E., and Tsyrenzhapov, M. B., A Means for Assessing the Functional State of the Hemostatic System, RF Patent No. 2282855 (2004).

  8. Tyutrin, I. I., Zhukov, E. L., and Slizevich, D. S., A Database for Values Characterizing the State of the Hemostatic Potential in Essentially Healthy Volunteers in the Siberian Population, Inventor’s Certificate No. 2019620555 (2019).

  9. Karkouti, K., Callum, J., Wijeysundera, D., Rao, V., Crowther, M., Grocott, H., and Pinto, R., “Point-of-care hemostatic testing in cardiac surgery: A stepped-wedge clustered randomized controlled trial,” Circulation, 134 (2016).

  10. Aksel’rod, B. A., “The POCT approach in the practice of anesthesiology and resuscitation,” in: Russian Forum of Anesthesiologists and Resuscitation Physicians, FARR-2019 [in Russian], Moscow, October 18–20, 2019; http://mednord-t.ru/wp-content/uploads/2020/03/POCT.pdf ().

  11. Brazhnikova, O. V., Gevelya, N. V., and Maikova I. D., “Pediatrics. Typical errors at the preanalytical stage of laboratory investigations,” Concilium Medicum, No. 4, Supplement, 84–90 (2017).

  12. Li, L., Sytnik, Yu. D., Gubarev, F. A., and Pekker, Y. S., “Evaluation of blood plasma coagulability by laser speckle correlation,” Biomed. Eng., 52, 177–180 (2018).

    Article  Google Scholar 

  13. Fanaskova, E. V., Gruzdeva, O. V., Akbasheva, O. E., Tyutrin, I. I., Penskaya, T. Yu., Uchasova, E. G., Dyleva, Yu. A., and Barbarash O. L., “The possibility of using low-frequency piezothromboelastography for assessment of the hemostatic potential of the blood in coronary bypass surgery on the background of long-term aspirin treatment,” Byul. Sib. Med., No. 3, 145–155 (2017).

    Article  Google Scholar 

  14. Tyutrin, I. I., Shpisman, M. N., and Shipakov, V. E., “ Piezoelectric vibration hemocoagulography as a method for evaluating the functional status of the hemostatic system,” Biomed. Eng., 27, 252–256 (1993).

    Article  Google Scholar 

  15. https://www.arduino.cc/ (accessed March 17, 2020).

  16. http://mednord-t.ru/informaciya/ (accessed March 17, 2020).

Download references

Author information

Authors and Affiliations

  1. National Research Tomsk Polytechnic University, Tomsk, Russia

    E. L. Zhukov & F. A. Gubarev

  2. OOO Mednord_Tekhnika, Tomsk, Russia

    E. L. Zhukov & I. I. Tyutrin

  3. Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia

    I. I. Tyutrin

Authors
  1. E. L. Zhukov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. A. Gubarev
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. I. Tyutrin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. L. Zhukov.

Additional information

Translated from Meditsinskaya Tekhnika, Vol. 54, No. 5, Sep.-Oct., 2020, pp. 35-38.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhukov, E.L., Gubarev, F.A. & Tyutrin, I.I. A Portable Device for Rapid Assessment of the Functional State of the Hemostasis System. Biomed Eng 54, 345–349 (2021). https://doi.org/10.1007/s10527-021-10036-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10527-021-10036-8

Search

Navigation